Tangeretin offers neuroprotection against colchicine-induced memory impairment in Wistar rats by modulating the antioxidant milieu, inflammatory mediators and oxidative stress in the brain tissue [PDF]
BMC Complementary Medicine and TherapiesBackground Tangeretin, a flavone compound (O-polymethoxylated) naturally present in tangerine and other citrus peels has demonstrated effectiveness as an anti-inflammatory and neuroprotective agent in several disease model.
Olalekan Bukunmi Ogunro +4 more
doaj +3 more sources
Tangeretin Suppresses Fumonisin Production by Modulating an NmrA- and HSCARG-like Protein in Fusarium verticillioides [PDF]
Journal of FungiFumonisins are polyketide-derived mycotoxins posing significant health threats to humans and animals. Among these, fumonisin B1 (FB1) is the most prevalent mycotoxin, primarily produced by Fusarium verticillioides, especially in maize and its derived ...
Liuqing Wang +6 more
doaj +3 more sources
The impact of tangeretin combined with whey protein on exercise-induced bronchoconstriction in professional athletes: a placebo-controlled trial [PDF]
Journal of the International Society of Sports NutritionBackground Exercise-induced bronchoconstriction (EIB) is highly prevalent in athletes. The objective of this study was to assess the therapeutic efficacy of daily tangeretin combined with whey protein supplementation over a period of 4 weeks in ...
Zhi Cao +4 more
doaj +3 more sources
The impact of tangeretin combined with whey protein supplementation on body composition and hormonal profiles in elite sprinters: A double-blind RCT [PDF]
Journal of Exercise Science & FitnessObjective: This study explored the combined effects of tangeretin and whey protein on serum testosterone and cortisol in competitive athletes. Methods: In a double-blind,controlled trial, 24 elite sprinters were divided into two groups: an experimental ...
Zhi Cao, Zheng Zhang, Meng Liu
doaj +3 more sources
Effect of tangeretin on cisplatin-induced oxido-inflammatory brain damage in rats. [PDF]
J Cell Mol MedAbstractCisplatin (CIS) is a platinum‐derived chemotherapeutic agent commonly utilized in the treatment of various malignant tumours. However, anticancer doses of the drug cause serious damage to the brain. This study aimed to determine the potential protective effects of tangeretin, which has antioxidant and anti‐inflammatory properties, in cisplatin ...
Cicek B +8 more
europepmc +5 more sources
Plant Biotechnology Journal, EarlyView.Tangeretin has been known as a polymethoxylated flavone conferring both phytoprotection and nutraceutical value, but cryoprotective roles and molecular regulation of tangeretin under abiotic stresses remain largely unexplored.
Peng Xiao +8 more
semanticscholar +2 more sources
Tangeretin inhibits airway inflammatory responses by reducing early growth response 1 (EGR1) expression in mice exposed to cigarette smoke and lipopolysaccharide [PDF]
HeliyonBackground: Tangeretin, a natural polymethoxyflavone compound, possesses potent anti-inflammatory activity that improves respiratory inflammation in chronic obstructive pulmonary disease (COPD).
Eun Sol Oh +10 more
doaj +2 more sources
Progress of Researches on Pharmacological Effects and Bioavailability of Tangeretin
Journal of Oleo ScienceTangeretin is one of the most abundant polymethoxyflavones in citrus peel and its pharmacological effects are extremely rich. However, due to its poor solubility, bitter taste and poor oral bioavailability, the oral administration of tangeretin is still limited, which seriously limits its application in industrial production.
Wanqing, Wang +3 more
openaire +3 more sources
Pharmacokinetics, bioavailability, tissue distribution and excretion of tangeretin in rat
Journal of Food and Drug Analysis, 2018 Tangeretin, 4',5,6,7,8-pentamethoxyflavone, is one of the major polymethoxyflavones (PMFs) existing in citrus fruits, particularly in the peels of sweet oranges and mandarins. Tangeretin has been reported to possess several beneficial bioactivities including anti-inflammatory, anti-proliferative and neuroprotective effects.
Wei-Lun Hung +2 more
exaly +4 more sources
LifeNeuroinflammation is the major cause of neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease. Currently available drugs present relatively low efficacy and are not capable of modifying the course of the disease or delaying its ...
Irshad Wani +7 more
doaj +2 more sources