Results 21 to 30 of about 4,478 (234)

Tangeretin Improves the Memory of Swiss Mice, Suggesting Potential Molecular Interventions Through Animal Behavior Assessments and In Silico Studies

Brain and Behavior
Introduction Tangeretin (TAN), a polymethoxylated flavone from citrus peels, exhibits neuroprotective, anti‐inflammatory, and antioxidant properties. This study aims to evaluate the memory‐enhancing effects of TAN in Swiss mice and explore its potential ...
Md. Sakib Al Hasan, Mohd Shahnawaz Khan, Arusha Ayub, Raihan Chowdhury, Emon Mia, Md. Shadin, Md. Showkot Akbor, Muhammad Torequl Islam, Md. Shimul Bhuia   +8 more
doaj   +2 more sources

Tangeretin inhibits hepatocellular carcinoma proliferation and migration by promoting autophagy-related BECLIN1

Cancer Management and Research, 2019
Jiao Zheng,1 Yaqin Shao,1 Yu Jiang,2 Fang Chen,2 Sulai Liu,3 Nanhui Yu,2 Dandan Zhang,2 Xiehong Liu,2 Lianhong Zou21Drug Clinical Trial Institution Department, Hunan Provincial People’s Hospital, First Affiliated Hospital of Hunan Normal University,
Zheng J, Shao Y, Jiang Y, Chen F, Liu S, Yu N, Zhang D, Liu X, Zou L   +8 more
doaj   +3 more sources

The Chemopreventive Effects of The Combination Between Tea Leaf and Mandarine Peel Extract on Breast Cancer Cell [PDF]

Journal of Fundamental and Applied Pharmaceutical Science, 2020
The number of breast cancer patients is increasing high in the world. This study aims to determine the chemopreventive effect of a combination of ethanolic extracts of tea leaves and mandarin peel in silico and in vitro on T47D breast cancer cells ...
Ega Hida Prabowo, Rifki Febriansah
doaj   +3 more sources

Tangeretin in the Treatment of Pulmonary Fibrosis: Current Advances and Future Perspectives

Current Molecular Pharmacology
Pulmonary fibrosis seriously endangers human health, with its incidence and mortality rates steadily increasing. Current treatment methods have limitations. This review focused on the research progress and future prospects of tangeretin in the treatment of pulmonary fibrosis. Tangeretin, a compound derived from the peel of citrus fruits, has garnered
Ling-Jie, Wang, Peng-Fei, Guo, Yi-Zhao, Chen, Hong-Wang, Yan, Xue-Lin, Zhang   +4 more
openaire   +3 more sources

Tangeretin inhibits fungal ferroptosis to suppress rice blast [PDF]

Journal of Integrative Plant Biology, 2021
AbstractFlavonoids are polyphenolic secondary metabolites that function as signaling molecules, allopathic compounds, phytoalexins, detoxifying agents and antimicrobial defensive compounds in plants. Blast caused by the fungusMagnaporthe oryzaeis a serious disease affecting rice cultivation.
Meiling Liang, Huijuan Ye, Qing Shen, Xianya Jiang, Guobing Cui, Wenxiang Gu, Lian‐Hui Zhang, Naweed I. Naqvi, Yi Zhen Deng   +8 more
openaire   +2 more sources

Tangeretin Mitigates Trimethylamine Oxide Induced Arterial Inflammation by Disrupting Choline–Trimethylamine Conversion through Specific Manipulation of Intestinal Microflora

Molecules
Previous studies have revealed the microbial metabolism of dietary choline in the gut, leading to its conversion into trimethylamine (TMA). Polymethoxyflavones (PMFs), exemplified by tangeretin, have shown efficacy in mitigating choline-induced ...
Yu Cao, Changlong Leng, Kuan Lin, Youwei Li, Meiling Zhou, Mei Zhou, Xiji Shu, Wei Liu   +7 more
doaj   +2 more sources

Antidepressant-Like Effect of the Polymethoxylated Flavone Tangeretin from Citrus Peels: The Role of Serotonergic Mechanisms

Psychiatry and Behavioral Sciences
Objective: Depression is a mood disorder characterized by a set of emotional, cognitive, physical and behavioral symptoms. Low response rate to antidepressant treatment in patients with depression, late onset of action, side effects due to long-term drug
Ozgur Devrim Can, Nesime İnci Guner
doaj   +2 more sources

Citrus Flavonoids for Cystic Fibrosis Treatment. [PDF]

Chembiochem
Studies conducted since the late 1990s show substantial activity of selected citrus flavonoids as cystic fibrosis transmembrane conductance regulator (CFTR) membrane protein activators. The thesis of this work is that aptly formulated citrus flavonoids hold sigificant potential for developing a multitarget treatment of cystic fibrosis combining in a ...
Pagliaro M, Di Sano C, D'Anna C, Li Petri G, Angellotti G, Ciriminna R.   +5 more
europepmc   +2 more sources

Characterization of tangeretin as an activator of nuclear factor erythroid 2-related factor 2/antioxidant response element pathway in HEK293T cells

Current Research in Food Science, 2023
Numerous studies have reported that tangeretin is a polymethoxylated flavone with a variety of biological activates, but little research has been done on the antioxidant mechanism of tangeretin.
Chengyu Lv, Yuqiu Li, Rong Liang, Wei Huang, Yechen Xiao, Xinqi Ma, Yongjun Wang, Haoyang Zou, Fen Qin, Chang Sun, Tiezhu Li, Jie Zhang   +11 more
doaj   +1 more source

Incipient citrus polymethoxylated flavone Tangeretin as anticancer drug candidate: Mechanistic insights, limitations and possible solutions

Advances in Cancer Biology - Metastasis, 2021
Tangeretin is one of the many polymethoxyflavones (PMFs) mostly found in fruits and fruit peels of citrus plants. In view of its importance as a nutraceutical it has received extensive scientific scrutiny with regards to its suspected diverse ...
Alex Boye, Imad Ahmad, Sajad Fakhri, Yaseen Hussain, Haroon Khan   +4 more
doaj   +1 more source