Results 81 to 90 of about 4,478 (234)

L‐Quebrachitol Enhances Sedative Effect of Diazepam Through GABAergic Pathway: Animal and Computational Studies

Brain and Behavior, Volume 16, Issue 1, January 2026.
L‐quebrachitol (LQL) significantly enhanced the sedative effects of diazepam in thiopental sodium‐induced chicks by reducing sleep latency and prolonging duration. Molecular docking revealed LQL's interaction with GABAA receptor (α1 and β2 subunits), supporting a GABAergic mechanism and highlighting its potential as a safe, natural sedative agent ...
Asifa Asrafi, Mohammad Aslam, Md. Sakib Al Hasan, Mohammed Burhan Uddin, Emon Mia, Mohammad Y. Alshahrani, Sumaya Akter Bithi, Mst. Sumaia Akter, Md. Arif Hossain, Md. Torequl Islam   +9 more
wiley   +1 more source

Potential senotherapeutic candidates and their combinations derived from transcriptional connectivity and network measures

Informatics in Medicine Unlocked, 2022
Cellular senescence, a state of permanent cell cycle arrest, is associated with organismal aging and malfunctioning. Various attempts have been made to find a unified gene signature for all senescence models in every cell type. However, with more studies
Amirhossein Nayeri Rad, Golnaz Shams, Roberto A. Avelar, Mohammad Hossein Morowvat, Younes Ghasemi   +4 more
doaj   +1 more source

Deficit irrigation and maturation stage influence quality and flavonoid composition of ‘Valencia’ orange fruit [PDF]

, 2016
BACKGROUND:Effects of continuous deficit irrigation (DI) and partial rootzone drying (PRD) treatments (50%ETc) in comparison with full irrigation (CI, 100% ETc) were investigated during ‘Valencia’ orange fruit maturation.
DI STEFANO, Vita, Grilo, FS, LO BIANCO, Riccardo   +2 more
core   +1 more source

Improving Bioavailability of 5‐Hydroxy Tangeretin by Food Grade Nanoemulsions

The FASEB Journal, 2012
Our previous studies demonstrated potent anti‐cancer effects of 5‐hydroxy tangeretin (5HT, a citrus flavonoid). However, high hydrophobicity of 5HN results in poor bioavailability, which has greatly limited its utilization as a nutraceutical. Herein, we investigated the possibility of encapsulating 5HN within food‐grade nanoemulsions to improve its ...
jinkai zheng, Yan Li, Noppawat Charoensinphon, Wasamon Nutakul, Ping Dong, Peiju Qiu, David Julian McClements, Hang Xiao   +7 more
openaire   +1 more source

Neuroprotective effect of tangeretin against chromium-induced acute brain injury in rats: targeting Nrf2 signaling pathway, inflammatory mediators, and apoptosis

InflammoPharmacology, 2023
Potassium dichromate (PD) is an environmental xenobiotic commonly recognized as teratogenic, carcinogenic, and mutagenic in animals and humans. The present study was conducted to investigate the role of tangeretin (TNG) as a neuro-protective drug against
Ahmed A Sedik, Rania Elgohary
semanticscholar   +1 more source

Seasonal Effect of Ultraviolet Irradiation on Polymethoxyflavone and Hesperidin Content in Ponkan and Tachibana Flavedo

HortScience, 2020
Ponkan (Citrus reticulate) and Tachibana (Citrus tachibana) contain large amounts of polymethoxyflavones (PMFs). To produce highly functional food with high potential, it is important to develop technologies to increase their PMF content.
Ittetsu Yamaga , Sakura Hamasaki
doaj   +1 more source

Tangeretin alleviates inflammation and oxidative response induced by spinal cord injury by activating the Sesn2/Keap1/Nrf2 pathway

Phytotherapy Research
Spinal cord injury (SCI) is a severe disabling disease that is characterized by inflammation and oxidative reactions. Tangeretin has been shown to possess significant antioxidant and anti‐inflammatory activities. The Keap1/Nrf2 pathway, downstream of the
Birong Peng, Jinwei Hu, Yuanfang Sun, Yating Huang, Qingshan Peng, Weiwen Zhao, Wenning Xu, Lixin Zhu   +7 more
semanticscholar   +1 more source

Nutritional Content, Phytochemical Composition, and Physicochemical Properties of Different Quinoa (Chenopodium quinoa Willd.) Seed Varieties

Cereal Chemistry, Volume 103, Issue 1, Page 93-109, January/February 2026.
ABSTRACT Background and Objectives Quinoa (Chenopodium quinoa Willd.) is a pseudocereal with documented benefits for human health. The macronutrient composition and phytochemical content of the grain are known to vary depending on the variety and the growing location.
Vassilios Raikos, Shirley De Lima Sampaio, Helen E. Hayes, Gary J. Duncan, Donna Henderson, Nicholas J. Vaughan, Wendy R. Russell, Madalina Neacsu   +7 more
wiley   +1 more source

Tangeretin Inhibits Hepatocellular Carcinoma Proliferation and Migration by Promoting Autophagy-Related BECLIN1 [Retraction]

Cancer Management and Research, 2023
Zheng J, Shao Y, Jiang Y, et al. Cancer Manag Res. 2019;11:5231–5242. We, the Editors and Publisher of Cancer Management and Therapy, have retracted the following article.
Zheng J, Shao Y, Jiang Y, Chen F, Liu S, Yu N, Zhang D, Liu X, Zou L   +8 more
doaj  

Dual‐Pathway Defense: Ultramicro‐Pulverised Powder of Polygonum chinense L. and Atractylodes rhizome (PAUP) Rescues Broilers From E. coli‐Triggered Liver Injury Through Modulation of Oxidative Stress and Inflammation

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Reduced Antibiotic residues and resistance concerns: Offers a potential natural alternative to antibiotics for combating E. coli infections in poultry. Provided safer poultry food products: By enhancing liver function, restoring weight gain, and improving feed efficiency, PAUP supports the production of healthier chickens, ultimately contributing to ...
Jia‐Ci Cai, Yan‐Na Guo, Shao‐Shan Liang, Yan Liu, Fu‐Qiang Huang, Qi‐Peng Lv, Lan‐Yi Zhang, Yi Qin, Xiao‐Jing Chen, Yu‐Xin Liang, Yong‐Ming He, Lu‐Ping Tang   +11 more
wiley   +1 more source