Results 141 to 150 of about 9,324,018 (299)
British Journal of Clinical Pharmacology, EarlyView.N‐of‐1 trials offer a unique and rigorous methodology for evaluating individualized treatment responses, particularly within the context of personalized medicine. This article provides a comprehensive explanation of the conceptual and methodological underpinnings of N‐of‐1 trials, with particular emphasis on statistical techniques and considerations ...
Marcos Clint Leal De Carvalho +5 more
wiley +1 more source
Studies on the Protein Defect in Tangier Disease [PDF]
, 1972 Samuel E. Lux +3 more
openalex +1 more source
BMEMat, EarlyView.Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen +7 more
wiley +1 more source
An evaluation of the utilization of remote sensing in resource and environmental management of the Chesapeake Bay region [PDF]
A nine-month study was conducted to assess the effectiveness of the NASA Wallops Chesapeake Bay Ecological Program in remote sensing. The study consisted of a follow-up investigation and information analysis of actual cases in which remote sensing was ...
Fuller, D. B. +2 more
core +1 more source
Impaired Platelet Activation in Familial High Density Lipoprotein Deficiency (Tangier Disease) [PDF]
, 2004 Jerzy–Roch Nofer +9 more
openalex +1 more source
BMEMat, EarlyView.A nano‐drug based on retinoic acid and calcium is developed, which can be rapily endocytosed by microglia and decomposed into small molecule/ion storms in lysosomes. This nano‐drug regulates microglial phenotype switching from M1 to M2 while indirectly guiding neuronal differentiation of endogenous neural stem cells, thereby ameliorating ...
Shuo Zhang +13 more
wiley +1 more source
Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond
BMEMat, EarlyView.Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad +8 more
wiley +1 more source
Biomaterial design strategies for enhancing mitochondrial transplantation therapy
BMEMat, EarlyView.Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source
Triple negative breast cancer in North of Morocco: clinicopathologic and prognostic features [PDF]
, 2016 core +1 more source
Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation
BMEMat, EarlyView.Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu +12 more
wiley +1 more source