Results 41 to 50 of about 9,324,018 (299)

Complex systems in the history of American English [PDF]

, 2014
Kretzschmar 2009 has demonstrated that language in use, speech as opposed to linguistic systems as usually described by linguists, satisfies the conditions for complex systems as defined in sciences such as physics, evolutionary biology, and economics ...
Kretzschmar, Jr., William A.
core   +1 more source

Reduction in apolipoprotein-mediated removal of cellular lipids by immortalization of human fibroblasts and its reversion by cAMP: lack of effect with Tangier disease cells

Journal of Lipid Research, 1999
High density lipoprotein (HDL) phospholipids and apolipoproteins remove cellular lipids by two distinct mechanisms, but their relative contribution to reverse cholesterol transport is unknown.
John F. Oram, Armando J. Mendez, James Lymp, Terrance J. Kavanagh, Christine L. Halbert   +4 more
doaj   +1 more source

Regulation and intracellular trafficking of the ABCA1 transporter

Journal of Lipid Research, 2001
The discovery of the role of the ATP-binding cassette transporter A1 (ABCA1) in mediating apolipoprotein A-I-mediated efflux has led to a dramatic increase in our knowledge of the molecular mechanisms involved in cholesterol efflux and cellular ...
Silvia Santamarina-Fojo, Alan T. Remaley, Edward B. Neufeld, H. Bryan Brewer, Jr.   +3 more
doaj   +1 more source

Release of cholesterol-rich particles from the macrophage plasma membrane during movement of filopodia and lamellipodia. [PDF]

, 2019
Cultured mouse peritoneal macrophages release large numbers of ~30-nm cholesterol-rich particles. Here, we show that those particles represent fragments of the plasma membrane that are pulled away and left behind during the projection and retraction of ...
Fong, Loren G, He, Cuiwen, Heizer, Patrick J, Hu, Xuchen, Jiang, Haibo, Jung, Rachel S, Tontonoz, Peter, Tu, Yiping, Weston, Thomas A, Wohlschlegel, James A, Young, Brian D, Young, Stephen G   +11 more
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Exome sequencing in suspected monogenic dyslipidemias [PDF]

, 2015
Exome sequencing is a promising tool for gene mapping in Mendelian disorders.
Abifadel, M., AVERNA, Maurizio, Awan, Z., Boileau, C., CEFALU', Angelo Baldassare, Daly, M., Deo, R., Farlow, D., Fouchier, S., Freeman, M., Gabriel, S., Genest, J., Gupta, N., Haller, J., Hovingh, G., Kane, J., Kastelein, J., Kathiresan, S., Kawashiri, M., Larach, D., Mabuchi, H., Motazacker, M., Neale, B., Nickerson, D., Nohara, A., NOTO, Davide, Peloso, G., Pullinger, C., Rabès, J., Rader, D., Rich, S., Risman, M., Ruel, I., Shendure, J., Stitziel, N., Tada, H., Tarugi, P., Varret, M., Wilson, J., Yamagishi, M.   +39 more
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Platelet function and platelet lipid composition in the dyslipoproteinemias

Journal of Lipid Research, 1980
Blood platelets from eight patients with hyperbetalipoproteinemia (type II) were more reactive to aggregating agents in vitro than those of 13 type IV patients or 12 normal subjects. Platelets of two patients with abeta-lipoproteinemia were also slightly
K M Shastri, A C Carvalho, R S Lees
doaj   +1 more source

Isoproteins of human apolipoprotein A-II: isolation and characterization.

Journal of Lipid Research, 1983
In human serum, polymorphism of apoA-II predominantly in HDL3 could be demonstrated. HDL3-apoA-II was composed of four isoproteins, each with a molecular weight of 8600 (reduced form) and identical immunological properties. The isoproteins are designated
G Schmitz, K Ilsemann, B Melnik, G Assmann   +3 more
doaj   +1 more source

Measurement of apolipoprotein E and amyloid β clearance rates in the mouse brain using bolus stable isotope labeling [PDF]

, 2012
BACKGROUND: Abnormal proteostasis due to alterations in protein turnover has been postulated to play a central role in several neurodegenerative diseases.
Basak, Jacob M, Bateman, Randall J, Holtzman, David M, Jiang, Hong, Kim, Jungsu, Parsadanian, Maia, Patterson, Bruce W, Pyatkivskyy, Yuriy, Wildsmith, Kristin R   +8 more
core   +2 more sources

Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations

Journal of Lipid Research, 2003
The current model for reverse cholesterol transport proposes that HDL transports excess cholesterol derived primarily from peripheral cells to the liver for removal.
Federica Basso, Lita Freeman, Catherine L. Knapper, Alan Remaley, John Stonik, Edward B. Neufeld, Terese Tansey, Marcelo J.A. Amar, Jamila Fruchart-Najib, Nicholas Duverger, Silvia Santamarina-Fojo, H.Bryan Brewer, Jr.   +11 more
doaj   +1 more source

HDL: the yin-yang of cardiovascular disease [PDF]

Estudos epidemiológicos mostram relação inversa entre níveis plasmáticos de HDL-colesterol (HDL-C) e incidência de doença cardiovascular (DCV). O papel antiaterogênico da HDL é atribuído às suas atividades anti-inflamatória, antitrombótica e antioxidante,
LEANÇA, Camila Canteiro, NAKANDAKARE, Edna R., PASSARELLI, Marisa, QUINTÃO, Eder C. R.   +3 more
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