Results 81 to 90 of about 9,324,018 (299)
Advanced Science, EarlyView.SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He +5 more
wiley +1 more source
ABCA1: the gatekeeper for eliminating excess tissue cholesterol
Journal of Lipid Research, 2001 It is widely believed that HDL functions to transport cholesterol from peripheral cells to the liver by reverse cholesterol transport, a pathway that may protect against atherosclerosis by clearing excess cholesterol from arterial cells.
John F. Oram, Richard M. Lawn
doaj +1 more source
AI‐Assisted Bioelectronics for Personalized Health Management
Advanced Electronic Materials, EarlyView.Recent advances in artificial intelligence (AI)‐assisted bioelectronics, including materials, device fabrication, working mechanisms, AI‐hardware integration, and proof‐of‐concept applications in digital health management, are summarized. The emergence of AI‐assisted bioelectronic systems and potential solutions to existing challenges are discussed ...
Huiwen Xiong +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.Targeted covalent inhibitors (TCI) containing cyclic imine warheads react with tyrosine and tryptophan residues via the Mannich reaction. These cyclic imine warheads show comparable reaction kinetics to cysteine‐reactive electrophiles commonly used in TCIs.
Sijie Wang +6 more
wiley +2 more sources
The complete contents of 'The Mediterranean Naturalist', a periodical published in Malta between 1891 and 1893 [PDF]
, 1999 An account is given of the journal "The Mediterranean Naturalist', edited and published by John Henry Cooke (1862- 1933) towards the end of the nineteenth century.
Schembri, Patrick J.
core
Mechanistic convergence and shared therapeutic targets in Niemann‐Pick disease [PDF]
, 2019 Niemann‐Pick disease type C (NPC) and Tangier disease are genetically and clinically distinct rare inborn errors of metabolism. NPC is caused by defects in either NPC1 or NPC2; whereas Tangier disease is caused by a defect in ABCA1.
Andriaenssens, Elias +12 more
core +2 more sources
Biomedical Journal of Scientific & Technical Research, 2018 We reported two cases being treated with HRT for the past 7~11 years presenting no progression in atherosclerosis. The first case was diagnosed of having CETP deficiency (homozygosity type) and fibromyalgia at the age of 52. The HDL-cholesterol level was
K. Miyachi +10 more
semanticscholar +1 more source
Guidelines for the Anti‐Obesity Assays of Food Bioactives in Caenorhabditis elegans
AgriFood: Journal of Agricultural Products for Food, EarlyView.This Guideline uses Caenorhabditis elegans as a model organism to systematically explain and summarize the research strategies and experimental methods for the anti‐obesity effects of food bioactives. ABSTRACT The obesity has become a global public health problem and is closely related to a variety of chronic diseases.
Rui Lu
wiley +1 more source
Measurement of human high density lipoprotein apolipoprotein A-I in serum by radioimmunoassay
Journal of Lipid Research, 1976 A sensitive and specific double antibody radioimmunoassay for the major apolipoprotein (apo A-I) of human serum high density lipoprotein (HDL) was developed.
J B Karlin +4 more
doaj +1 more source
High-density lipoprotein, beta cells, and diabetes . [PDF]
, 2014 High-density lipoproteins (HDLs) exert a series of potentially beneficial effects on many cell types including anti-atherogenic actions on the endothelium and macrophage foam cells. HDLs may also exert anti-diabetogenic functions on the beta cells of the
von Eckardstein, A., Widmann, C.
core +2 more sources