Results 11 to 20 of about 5,911 (150)

Investigating the role of a Tannerella forsythia HtrA protease in host protein degradation and inflammatory response [PDF]

Frontiers in Oral Health
IntroductionDegradation of host proteins by bacterial proteases leads to the subversion of the host response and disruption of oral epithelial integrity, which is considered an essential factor in the progression of periodontitis.
Susanne Bloch, Susanne Bloch, Fiona F. Hager-Mair, Johanna Bacher, Johanna Bacher, Markus B. Tomek, Bettina Janesch, Oleh Andrukhov, Christina Schäffer   +8 more
doaj   +2 more sources

Utilization of different MurNAc sources by the oral pathogen Tannerella forsythia and role of the inner membrane transporter AmpG [PDF]

BMC Microbiology, 2020
Background The Gram-negative oral pathogen Tannerella forsythia strictly depends on the external supply of the essential bacterial cell wall sugar N-acetylmuramic acid (MurNAc) for survival because of the lack of the common MurNAc biosynthesis enzymes ...
Valentina M. T. Mayer, Markus B. Tomek, Rudolf Figl, Marina Borisova, Isabel Hottmann, Markus Blaukopf, Friedrich Altmann, Christoph Mayer, Christina Schäffer   +8 more
doaj   +2 more sources

Screening and characterization of aptamers recognizing the periodontal pathogen Tannerella forsythia [PDF]

FEBS Open Bio
Periodontal disease is one of the most common forms of inflammation. It is currently diagnosed by observing symptoms such as gingival bleeding and attachment loss.
Danuta Mizgalska, Stanisław Malicki, Anna Golda, Barbara Chruścicka‐Smaga, Jan Potempa   +4 more
doaj   +2 more sources

ASSOCIATION OF THE BONE LOSS WITH MAIN CLINICAL AND MICROBIOLOGICAL PARAMETERS IN CHRONIC PERIODONTITIS [PDF]

Journal of IMAB, 2014
Literature data have reported that certain Gram-negative anaerobe bacteria from the subgingival environment are important etiological agents of chronic periodontal disease.
Velitchka Dosseva-Panova, Christina Popova, Angelina Kisselova-Yaneva, Vladimir E. Panov   +3 more
doaj   +1 more source

The first study to detect co-infection of Entamoeba gingivalis and periodontitis-associated bacteria in dental patients in Taiwan

Journal of Microbiology, Immunology and Infection, 2021
Periodontitis, an inflammatory disease of the oral cavity, was caused by microbes from bacteria to protozoa. In this study, we detected protozoa, Entamoeba gingivalis and other three common pathogenic bacteria, Porphyromonas gingivalis, Treponema ...
Jian Ming Huang, Chun Chan Ting, Yu Chun Chen, Kuo Yuan, Wei Chen Lin   +4 more
doaj   +1 more source

Single cell genomics of uncultured, health-associated Tannerella BU063 (Oral Taxon 286) and comparison to the closely related pathogen Tannerella forsythia. [PDF]

PLoS ONE, 2014
The uncultivated bacterium Tannerella BU063 (oral taxon 286) is the closest relative to the periodontal pathogen Tannerella forsythia, but is not disease-associated itself.
Clifford J Beall, Alisha G Campbell, Daniel M Dayeh, Ann L Griffen, Mircea Podar, Eugene J Leys   +5 more
doaj   +1 more source

Unexpected lower level of oral periodontal pathogens in patients with high numbers of systemic diseases [PDF]

PeerJ, 2023
Background Periodontal disease is associated with systemic conditions such as diabetes, arthritis, and cardiovascular disease, all diseases with large inflammatory components.
Michael T. Shen, Betti Shahin, Zhengjia Chen, Guy R. Adami   +3 more
doaj   +2 more sources

A General Protein O-Glycosylation Gene Cluster Encodes the Species-Specific Glycan of the Oral Pathogen Tannerella forsythia: O-Glycan Biosynthesis and Immunological Implications

Frontiers in Microbiology, 2018
The cell surface of the oral pathogen Tannerella forsythia is heavily glycosylated with a unique, complex decasaccharide that is O-glycosidically linked to the bacterium’s abundant surface (S-) layer, as well as other proteins.
Markus B. Tomek, Daniel Maresch, Markus Windwarder, Valentin Friedrich, Bettina Janesch, Kristina Fuchs, Laura Neumann, Irene Nimeth, Nikolaus F. Zwickl, Juliane C. Dohm, Arun Everest-Dass, Daniel Kolarich, Heinz Himmelbauer, Friedrich Altmann, Christina Schäffer   +14 more
doaj   +1 more source

KLIKK proteases of Tannerella forsythia: putative virulence factors with a unique domain structure

Frontiers in Microbiology, 2015
Comparative genomics of virulent Tannerella forsythia ATCC 43037 and a close health-associated relative, Tannerella BU063, revealed, in the latter, the absence of an entire array of genes encoding putative secretory proteases that possess a nearly ...
Miroslaw eKsiazek, Danuta eMizgalska, Sigrum eEick, Ida B Thøgersen, Jan J Enghild, Jan ePotempa, Jan ePotempa   +6 more
doaj   +1 more source

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Periodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis, Daniel Belstrøm, Sigrun Eick, Ulvi K. Gursoy, Anders Johansson, Eija Könönen   +5 more
wiley   +1 more source