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ChemInform Abstract: TOTALSYNTH. VON TANSHINON‐I, TANSHINON‐II UND CRYPTOTANSHINON

Chemischer Informationsdienst. Organische Chemie, 1970
AbstractDie Diels‐Alder‐Reaktion des Diens (I) mit dem aus 3‐Methyl‐4‐hydroxybenzofuran durch milde Oxidation erhältlichen Chinon (II) liefert nur das Addukt (III), das durch Luftoxidation in Isotanshinon‐II (IV) übergeführt wird.
YOSHINOBU INOUYE, HIROSHI KAKISAWA
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Synthesis of tanshinones

Tetrahedron, 1971
Abstract Tanshinone-II and cryptotanshinone have been synthesized from 1,2,4-trimethoxybenzene by fourteen steps.
M. Tateishi, T. Kusumi, H. Kakisawa
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Total Synthesis of Tanshinone I

Journal of Natural Products, 2017
A novel total synthesis of tanshinone I (1) via the intermediate 3-hydroxy-8-methyl-1,4-phenanthrenedione (8) is described. The low overall yields and the use of expensive reagents in the synthesis process were minimized by the use of the Diels-Alder reaction to directly construct the 1,4-phenanthrenedione scaffold, providing tanshinone I (1) in only ...
Nan Wu   +4 more
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Studies on the spectroscopic behavior of cryptotanshinone, tanshinone IIA, and tanshinone I

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2004
A comparative study on the spectroscopic behavior of cryptotanshinone (CTan), tanshinone IIA (Tan IIA), and tanshinone I (Tan I) has been investigated, including UV-Vis absorption, low temperature phosphorescence (LTP), low temperature fluorescence (LTF), paper substrate-room temperature phosphorescence (PS-RTP), paper substrate-room temperature ...
Jun-Fen, Li   +4 more
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Total synthesis of tanshinone IIA

Tetrahedron Letters, 2020
Abstract A novel synthetic route toward tanshinone IIA has been developed. Key steps involve a base mediated furan ring formation, and an acyloin condensation reaction to construct the ortho-quinone ring.
He Huang   +4 more
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Tanshinone IIA in Acute Promyelocytic Leukemia

The American Journal of the Medical Sciences, 2012
The prognosis of acute promyelocytic leukemia (APL) has been significantly improved by the use of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO). However, the utility of these drugs is limited by resistance to ATRA and the side effects of ATO.
Jian, Li   +3 more
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Isolation and Bioactivity of New Tanshinones

Journal of Natural Products, 1987
Two new diterpenoids, designated neocryptotanshinone and isotanshinone IIB, have been isolated from "Tan-Shen," the root of Salvia miltiorrhiza, together with a known compound, danshexinkun A. Their structures are established by spectral and physical data.
A R, Lee   +4 more
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A simply triggered peptide-based hydrogel as an injectable nanocarrier of tanshinone IIA and tanshinones

Chemical Communications, 2017
An easily self-assembled and gelated octa-peptide FHFDFHFD was chosen as a novel drug delivery system (DDS) for both tanshinone IIA and total tanshinone extract.
Yajun, Yin   +5 more
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