Tanshinone IIA alleviates LPS-induced acute kidney injury by inhibiting RIP3/Nrf2-mediated oxidative stress. [PDF]
Zhang S, Dong X, Chen G, Wang C.
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Research progress on the molecular mechanisms of tanshinone IIA in the treatment of cardiovascular and cerebrovascular diseases (Review). [PDF]
Pei W, Lu P, Ding C, Li Y, Li Y.
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Transformer-based graphs for drug-drug interaction with chemical knowledge embedding. [PDF]
Zhang J, Zhang X, Dai Y, Shao X, Fan X.
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Pharmacological Effects and Mechanisms of Tanshinone IIA in Bone Injury Repair. [PDF]
Hu W +6 more
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Tanshinones target drug-resistant tuberculosis: efficacy, selectivity, and potential mechanism of action. [PDF]
Polinário G +8 more
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Research Progress on <i>Salvia miltiorrhiza</i> Bioactive Components Regulating P-Selectin for Microcirculatory Improvement: Potential Implications in Acute Pancreatitis. [PDF]
Liu Y +9 more
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Correction to "Radix <i>Salvia miltiorrhiza</i> for Ankylosing Spondylitis: Determining Potential Inflammatory Molecular Targets and Mechanism Using Network Pharmacology". [PDF]
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AbstractSalvia miltiorrhiza is one of the most commonly used traditional Chinese medicines in the treatment of cardiovascular and cerebrovascular diseases. Cryptotanshinone (CTS), tanshinone IIA (Tan IIA), dihydrotanshinone I (diTan I), and tanshinone I (Tan I) are the main active compounds in the liposoluble extract of Salvia miltiorrhiza.
Daifei Wang +7 more
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Total Synthesis of Tanshinone I
Journal of Natural Products, 2017A novel total synthesis of tanshinone I (1) via the intermediate 3-hydroxy-8-methyl-1,4-phenanthrenedione (8) is described. The low overall yields and the use of expensive reagents in the synthesis process were minimized by the use of the Diels-Alder reaction to directly construct the 1,4-phenanthrenedione scaffold, providing tanshinone I (1) in only ...
Nan Wu +4 more
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