Results 111 to 120 of about 94,169 (259)

A Framework for a New Paradigm of Opioid Drug Tapering Using Adjunct Drugs

open access: yes
Michael A Veronin,1 Justin P Reinert2 1Department of Pharmaceutical Sciences and Health Outcomes The University of Texas at Tyler Ben and Maytee Fisch College of Pharmacy, Tyler, TX, USA; 2Department of Pharmacy Practice The University of Toledo College ...
Reinert JP, Veronin MA
core  

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro   +6 more
wiley   +1 more source

Opioid Tapering and Mental Health Crisis in Older Adults

open access: yes, 2022
Background: Opioid tapering and discontinuation have been increasing in recent years with the implementation of national prescribing guidelines. The study aimed to examine the relationship between opioid tapering and mental health crisis events in older ...
Maharjan, Shishir
core  

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru   +13 more
wiley   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Fibre optic tapering and shaping methods for special applications

open access: yes, 2023
The thesis deals with the tapering of optical fibres and the shaping of their ends. The thesis describes the fibre tapering and shaping methods and compares them in terms of advantages and disadvantages.
Hruška, Andrej
core  

Partial excisional tapering: Report of initial four cases of a novel modification of ureteroplasty for megaureter

open access: yesIJU Case Reports
Introduction We report our initial experience with a novel ureteroplasty technique that combines the advantages of excisional tapering and folding. Methods and cases Following dissection of the megaureter, the distal ureteral end was transected at a ...
Motohiro Taguchi   +2 more
doaj   +1 more source

The Role of Musculoskeletal Ultrasound in Biologic Drug Tapering and Relapse Monitoring: Findings from a One-Year Prospective Study in a Cohort of Rheumatoid Arthritis Patients in Sustained Clinical Remission

open access: yesDiagnostics
Objectives: To assess the role of musculoskeletal ultrasound (MSUS) in selecting patients with rheumatoid arthritis (RA) in sustained clinical remission, suitable for tapering of biologic therapy (BT), and monitoring for a subclinical relapse.
Zguro Batalov   +4 more
doaj   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro   +14 more
wiley   +1 more source

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus   +2 more
wiley   +1 more source

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