Results 31 to 40 of about 4,410,863 (269)
Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
The RAND Journal of Economics, 2008 We analyze a dynamic model of quantity competition, where firms continuously adjust their quantity targets, but incur convex adjustment costs when they do so. Quantity targets serve as a partial commitment device and, in equilibrium, follow a hump‐shaped pattern. The final equilibrium is more competitive than in the static analog.
Caruana, Guillermo, Einav, Liran
openaire +6 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom +15 more
wiley +1 more source
Connecting genetics and gene expression data for target prioritisation and drug repositioning
BioData Mining, 2018 Developing new drugs continues to be a highly inefficient and costly business. By repurposing an existing compound for a different indication, drug repositioning offers an attractive alternative to traditional drug discovery.
Enrico Ferrero, Pankaj Agarwal
doaj +1 more source
Experimental Study of Maritime Moving Target Detection Using Hitchhiking Bistatic Radar
Remote Sensing, 2022 Hitchhiking bistatic radar system takes the direct wave signal that is transmitted by the non-cooperative radar emitter as the reference to detect and analyze the target echo signal, so as to realize the positioning and tracking of the target. This radar
Jie Song +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld +5 more
wiley +1 more source
Nature Communications, 2021 How phase separation participates in mitophagy remains unclear. Here the authors show that Nur77 and p62/SQSTM1 through “head-to-head” and “tail-to-tail” interactions form membraneless condensates capable of sequestering dysfunctional mitochondria and ...
Shuang-zhou Peng +8 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo +9 more
wiley +1 more source
Research on Natural Gas Leakage and Explosion Mechanisms in a Container House
BuildingsAs unconventional building structures, container houses are now widely used in urban tourism to create characteristic buildings. Nowadays, natural gas accidents occur frequently in cities and towns; however, the development of laws and influencing ...
Yonghong Gao +6 more
doaj +1 more source
Moving nuclear receptor Nur77 to damaged mitochondria for clearance by mitophagy
Molecular & Cellular Oncology, 2018 Selective clearance of damaged mitochondria can reverse pathological status in chronic inflammatory diseases. We recently identified a critical role of nuclear receptor Nur77 and celastrol in priming inflamed mitochondria for autophagy through its ...
Mengjie Hu +4 more
doaj +1 more source