Results 41 to 50 of about 2,749,023 (281)

Image Formation of Azimuth Periodically Gapped SAR Raw Data with Complex Deconvolution

open access: yesRemote Sensing, 2019
The phenomenon of periodical gapping in Synthetic Aperture Radar (SAR), which is induced in various ways, creates challenges in focusing raw SAR data. To handle this problem, a novel method is proposed in this paper.
Yulei Qian, Daiyin Zhu
doaj   +1 more source

Phosphoproteomics and Multi-Omics for Oleanolic Acid Target Deconvolution: From Phosphorylation Signatures to Mechanistic Validation

open access: yesKinases and Phosphatases
Oleanolic acid (OA) is a pentacyclic triterpenoid with broad biological activity, but its primary molecular points of engagement remain incompletely resolved.
Andrzej Günther   +1 more
doaj   +1 more source

High-resolution Radar Imaging Using 2D Deconvolution with Sparse Echo Denoising

open access: yesLeida xuebao, 2018
This study proposes a high-resolution radar imaging method combined with the sparse low-rank matrix recovery technique and the deconvolution algorithm based on the matched filtering result.
Lu Xinfei   +3 more
doaj   +1 more source

Merging multi-omics with proteome integral solubility alteration unveils antibiotic mode of action

open access: yeseLife
Antimicrobial resistance is responsible for an alarming number of deaths, estimated at 5 million per year. To combat priority pathogens, like Helicobacter pylori, the development of novel therapies is of utmost importance.
Ritwik Maity   +8 more
doaj   +1 more source

Stability-based approaches in chemoproteomics

open access: yesExpert Reviews in Molecular Medicine
Target deconvolution can help understand how compounds exert therapeutic effects and can accelerate drug discovery by helping optimise safety and efficacy, revealing mechanisms of action, anticipate off-target effects and identifying opportunities for ...
Amy L. George   +3 more
doaj   +1 more source

Thermal Proteome Profiling to Identify Protein-ligand Interactions in the Apicomplexan Parasite Toxoplasma gondii

open access: yesBio-Protocol, 2021
Toxoplasma gondii is a single-celled eukaryotic parasite that chronically infects a quarter of the global population. In recent years, phenotypic screens have identified compounds that block parasite replication.
Alice Herneisen, Sebastian Lourido
doaj   +1 more source

Ma-Weber/Tutorial-Deconvolution: Initial release

open access: yes, 2020
Tutorial for the deconvolution of hydrophone measurement ...
Ma-Weber
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Ribifolones A–H, New Macrocyclic Diterpenes from Jatropha ribifolia, Their Cytotoxic Activity and Insights Supported by Network Pharmacology and Molecular Modeling

open access: yesMolecules
Belonging to the Euphorbiaceae family, the Jatropha genus is a promising source for the discovery of antitumor compounds. Jatropha ribifolia is a traditionally used species in folk medicine in the semi-arid region of Brazil, with a few chemical and ...
Thalisson Amorim de Souza   +12 more
doaj   +1 more source

Random Action of Compact Lie Groups and Minimax Estimation of a Mean Pattern [PDF]

open access: yes, 2011
This paper considers the problem of estimating a mean pattern in the setting of Grenander's pattern theory. Shape variability in a dataset of curves or images is modeled by the random action of elements in a compact Lie group on an infinite dimensional ...
Gadat, Sébastien   +3 more
core   +1 more source

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