Results 51 to 60 of about 1,554,918 (266)

Simple and sensitive electrochemical sensing of amethopterin by using carbon nanobowl/cyclodextrin electrode

Heliyon
Resulted from the severe side effects, the development of inexpensive, simple and sensitive method for amethopterin (ATP, an antineoplastic drug) is very important but it still remains a challenge.
Jian Wang, Xiuzhi Xu, Zhulai Li, Bin Qiu
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Target Detection in Sea Clutter Background via Deep Multi-Domain Feature Fusion

Remote Sensing
The complex and dynamic nature of the marine environment poses significant challenges for sea surface target detection. Traditional methods relying on single-domain features suffer from performance degradation under varying conditions.
Shichao Chen, Yue Wu, Wanghaoyu Sun, Hengli Yu, Feng Luo   +4 more
doaj   +1 more source

Visual Target Detection and Tracking Based on Kalman Filter

Havacılık ve Uzay Teknolojileri Dergisi, 2021
In this study, in order to prevent collision and target tracking in autonomous aircraft, Kalman filter with appropriate solutions for target detection and tracking problems are presented.
Gülay ÜNAL
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Unordered Stacked Pillbox Detection Algorithm Based on Improved YOLOv8

Big Data and Cognitive Computing
To enable fully automated medicine warehousing in intelligent pharmacy systems, accurately detecting disordered, stacked pillboxes is essential. This paper proposes a high-precision detection algorithm for such scenarios based on an improved YOLOv8 ...
Jiahang Pan, Rui Zhou, Jie Feng, Mincheng Wu, Xiang Wu, Hui Dong   +5 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

A lightweight and efficient ship detection model for complex maritime environments

Applied Ocean Research
Due to the complex and dense traffic in ports and their surrounding sea areas, along with the diverse and varying sizes of ships, ship detection faces significant challenges.
Yuankui Li, Ziqi Jia, Xinyu Zhang, Fang Yang, Xuefeng Yang   +4 more
doaj   +1 more source