Results 171 to 180 of about 4,123,279 (296)

From Target Engagement to Treatment Governance: The Evolving Role of Amyloid PET in Anti-Amyloid Therapy. [PDF]

Lancet Reg Health Eur
Filippi M, Cecchetti G, Ghirelli A, Spinelli EG, Rugarli G, Pisano S, Samanes Gajate AM, Chiti A, Agosta F.   +8 more
europepmc   +1 more source

Student Engagement Annual Report 2014-2015

, 2016
The Student Engagement annual report highlights achievements, challenges, opportunities and plans for the future. To find out more about the people, programs and opportunities found through Student Engagement, visit wichita.edu ...
Student Engagement, Student Affairs
core  

Advances in BRET probes for intracellular target engagement studies. [PDF]

Nat Chem Biol
Capener JL, Schwalm MP, Vasta JD, Michaud A, Teske KA, Marsiglia WM, Huber KVM, Dar AC, Knapp S, Axtman AD, Robers MB.   +10 more
europepmc   +1 more source

Public Engagement Metrics Committee Phase I Final Report

, 2012
The Public Engagement Metrics Committee was charged with establishing the University's metrics priorities for community-engaged initiatives. The Committee was to develop a prioritized, phased plan for instituting a comprehensive metrics system for ...
Office for Public Engagement
core  

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Biophysical Sensing Tools in Drug Discovery: Integrating Kinetics, Thermodynamics, Cellular Target Engagement and Structure. [PDF]

Sensors (Basel)
Balıkçı E, Akıl C.
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

NanoBRET Tracer Development for Class I Bromodomain Target Engagement in Live Cells. [PDF]

Bioconjug Chem
Sneddon MS, Tsou CJ, Fu X, Shelat AA, Pomerantz WCK.   +4 more
europepmc   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source