Results 71 to 80 of about 2,773,596 (266)
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen +10 more
wiley +1 more source
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau +8 more
wiley +1 more source
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
Multimodal targeting of glioma with functionalized nanoparticles
AbstractThe most common and aggressive primitive intracranial tumor of the central nervous system is the glioma. The blood–brain barrier (BBB) has proven to be a significant obstacle to the effective treatment of glioma. To effectively treat glioma, different ways have been used to cross the BBB to deliver drugs to the brain.
openaire +3 more sources
MATHEMATICAL MODEL OF THE METAL-CONSTRUCTION LINEAR CONVEYOR MASS WITH SUSPENDED GEARBOXING TAPE
Introduction. The article is devoted to the topical issue, which is related to the optimization of the linear part of the conveyor with a hanging load-carrying belt. In the work briefly reflect the main scientific and design developments of this conveyor
P. V. Boslovyak +2 more
doaj +1 more source
SUMOylation of the ubiquitin ligase component KEAP1 at K39 upregulates NRF2 and its target function in lung cancer cell proliferation. [PDF]
Yang H +11 more
europepmc +1 more source
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess +5 more
wiley +1 more source
Functionalized nanospheres for targeted delivery of paclitaxel
Targeted delivery of anti-cancer agents to cancer cells is a mature line of investigation that has yet to realize its full potential. In this study we report on the development of a delivery platform with the future goal of merging two thus far parallel methods for selective elimination of cancer cells: targeted nanospheres and pretargeted ...
Bushman, Jared +5 more
openaire +2 more sources
In the paper, we investigate two-criterion optimization problem: maximization of one target function and minimization of another target function. To solve the offered two-criterion problem, the method of the main criterion is applied.
L.Z. Khrushch
doaj +1 more source
Employing Explainable AI to Optimize the Return Target Function of a Loan Portfolio. [PDF]
Gramespacher T, Posth JA.
europepmc +1 more source

