Results 221 to 230 of about 226,271 (312)

<i>RPF2</i> regulates the protein kinase B/mammalian target of rapamycin pathway in the pathogenesis of <i>Helicobacter pylori</i>. [PDF]

World J Gastrointest Oncol
Hua YQ, Guo KX, Ni P, Wang D, An TY, Gao YY, Zhang RG.   +6 more
europepmc   +1 more source

Myelin Lipid Composition in the Central Nervous System Is Regionally Distinct and Requires Mechanistic Target of Rapamycin Signaling. [PDF]

Glia
Mather ML, Evangelou AV, Bourne JN, Macklin WB, Wood TL.   +4 more
europepmc   +1 more source

Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes, Daniel G. Di Luca, Connie Marras, Erik Boot, Ryan K.C. Yuen, Anthony E. Lang, Anne S. Bassett   +6 more
wiley   +1 more source

The target of rapamycin kinase is a positive regulator of plant fatty acid and lipid synthesis. [PDF]

Plant Physiol
Liu H, Blanford J, Shi H, Schwender J, Shanklin J, Zhai Z.   +5 more
europepmc   +1 more source

The Mammalian Target of Rapamycin

Journal of Pharmaceutical Care & Health Systems, 2015
openaire   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Activation of the Mammalian Target of Rapamycin Pathway in Endothelial Cells in Antiphospholipid Antibody-Positive Patients with Leg Ulcers. [PDF]

Int J Mol Sci
Kovács AL, Gyömörei C, Horváth S, Németh V, Dudley R, Nagy Z, Berki T, Lengyel Z, Gyulai R.   +8 more
europepmc   +1 more source

Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease

Neuroprotection, EarlyView.
Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García, Edgar Alvarado, Alejandro Cuevas, Laura Valverde, Eduardo Salinas, Kevin O'Hara‐Veintimilla, María Cruz Rodríguez‐Oroz, Miguel Germán Borda   +7 more
wiley   +1 more source

Phenylalanyl-tRNA synthetase subunit beta downregulation by spi1 proto-oncogene modulates lung adenocarcinoma progression and immune microenvironment via mammalian target of rapamycin pathway. [PDF]

J Chin Med Assoc
Wang Y, Zhou Y, Chen S, Huang J, Zhang C, Huang S, Pan Y, Huang X, Qin J, Lin S.   +9 more
europepmc   +1 more source

Caloric restriction‐mediated reproductive lifespan extension across multiple strains of the clonal aquatic plant Lemna turionifera

Oikos, EarlyView.
Lifespan extension due to caloric restriction (CR) is a well‐established aspect of animal senescence that has been observed in many taxa. Contrastingly, there is much less evidence in plants, even though it is straightforward to manipulate CR by restricting photosynthesis through reduction in light intensity.
Julian A. Ketler, Nicola M. Herman, Suzanne L. Chmilar, Robert A. Laird   +3 more
wiley   +1 more source