Results 111 to 120 of about 569,729 (301)

P115 ALBUMIN-TO-CREATININE RATIO IS ASSOCIATED WITH TARGET ORGAN DAMAGE IN HYPERTENSION

Artery Research, 2017
Purpose/Background/Objectives: Hypertension is associated with higher cardiovascular risk as well as several markers of subclinical target organ damage (TOD).
Losif Koutagiar, Charalambos Vlachopoulos, Dimitrios Terentes-Printzios, Nikolaos Loakeimidis, Christos Georgakopoulos, Konstantinos Aznaouridis, Panagiotis Xaplanteris, Athanasios Angelis, Dimitrios Tousoulis   +8 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Drug treatment of hypertension: focus on vascular health [PDF]

, 2016
Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C., Lang, Ninian N., Touyz, Rhian M.   +2 more
core   +1 more source

The Strain of Detecting Early Target Organ Damage in Hypertension

Journal of the American College of Cardiology, 2015
Hypertension contributes substantially to the burden of disease in developed nations and, increasingly, in the developing world [(1)][1]. Although recognition of high blood pressure (BP) seems simple, 20% to 30% of individuals have undiagnosed hypertension [(2)][2], and 50% to 70% of ...
Marwick, Thomas H., Venn, Alison J.
openaire   +2 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Study on Related Factors Between Essential Hypertension and Target Organ Damage

Huli yanjiu, 2001
To probe into the relationship between the pattern of blood pressure going up and the damage of the target organ heart, brain and kidney, 164 cases of essential hypertension （EH） were monitored with noninvasive ambulant blood pressure monitoring （ABPM ...
张学禹, 胡建红, 郭士英, 高明兰, 王敬萍, 薛树仁, 孔梅   +6 more
doaj  

Comprehensive assessment and management of hypertension in elderly patients: Addressing frailty and target organ damage

Journal of the Formosan Medical Association
The lifetime risk of incident hypertension is approximately 90%. Hypertension is the most important cardiovascular risk factor, and is readily modifiable.
Tzu-Chieh Lin, Ye-Hsu Lu, Chia-Ter Chao, Shin-Jing Lin, Po-Sheng Wu, Ding-Cheng Chan, Hsiang-Chun Lee   +6 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Central Hemodynamics and Target Organ Damage in Hypertension

The Tohoku Journal of Experimental Medicine, 2014
Recent advances in technology have enabled the noninvasive evaluation of pulsatile hemodynamics in the central aorta; namely, central pressure and flow measurements. The central blood pressure represents the true load imposed on the heart, kidney and brain, and the central blood flow influences the local flow into these vital organs.
openaire   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source