Results 11 to 20 of about 2,060,942 (128)
Thermodynamic restrictions on evolutionary optimization of transcription factor proteins [PDF]
, 2007 Conformational fluctuations are believed to play an important role in the process by which transcription factor proteins locate and bind their target site on the genome of a bacterium. Using a simple model, we show that the binding time can be minimized,
Adam +20 more
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, 2004 Publication in the conference proceedings of EUSIPCO, Viena, Austria ...
Alain Rakotomamonjy +2 more
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An alternative mode of microRNA target recognition [PDF]
Nature Structural & Molecular Biology, 2012 MicroRNAs (miRNAs) regulate mRNA targets through perfect pairing with their seed region (positions 2-7). Recently, a precise genome-wide map of miRNA interaction sites in mouse brain was generated by high-throughput sequencing and analysis of clusters of ~50-nucleotide mRNA tags cross-linked to Argonaute (Ago HITS-CLIP).
Chi, S. W. +2 more
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Language Modeling for Multi-Domain Speech-Driven Text Retrieval
, 2001 We report experimental results associated with speech-driven text retrieval, which facilitates retrieving information in multiple domains with spoken queries.
Fujii, Atsushi +2 more
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Target flexibility in molecular recognition [PDF]
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2005 Induced-fit effects are well known in the binding of small molecules to proteins and other macromolecular targets. Among other targets, protein kinases are particularly flexible proteins, so that such effects should be considered in attempts at structure-based inhibitor design for kinase targets.
openaire +3 more sources
Multi-target detection and recognition by UAVs using online POMDPs [PDF]
, 2013 This paper tackles high-level decision-making techniques for robotic missions, which involve both active sensing and symbolic goal reaching, under uncertain probabilistic environments and strong time constraints.
Lesire, Charles +2 more
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Continued effects of context reinstatement in recognition [PDF]
, 2015 The context reinstatement effect refers to the enhanced memory performance found when the context information paired with a target item at study is re-‐presented at test.
Hanczakowski, M, Macken, B, Zawadzka, K
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MicroRNAs: Target Recognition and Regulatory Functions [PDF]
Cell, 2009 MicroRNAs (miRNAs) are endogenous approximately 23 nt RNAs that play important gene-regulatory roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their posttranscriptional repression. This review outlines the current understanding of miRNA target recognition in animals and discusses the widespread impact of miRNAs on ...
openaire +4 more sources
Real sequence effects on the search dynamics of transcription factors on DNA [PDF]
, 2015 Recent experiments show that transcription factors (TFs) indeed use the facilitated diffusion mechanism to locate their target sequences on DNA in living bacteria cells: TFs alternate between sliding motion along DNA and relocation events through the ...
Bauer, Maximilian +3 more
core +2 more sources
The scene superiority effect: object recognition in the context of natural scenes [PDF]
, 2011 Four experiments investigate the effect of background scene semantics on object recognition. Although past research has found that semantically consistent scene backgrounds can facilitate recognition of a target object, these claims have been challenged
Yao, Richard
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