Results 111 to 120 of about 1,394,726 (329)

Seasonal variation in species composition and frequency of insecticide resistance alleles (kdr and ace-1r) in the Anopheles gambiae complex from an irrigated rice fields area in Western Burkina Faso [PDF]

, 2009
Monitoring of the spread of insecticide resistance in field vector populations is a prerequisite for the implementation of efficient and sustainable vector control strategies based on the use of insecticides. Screening for resistance alleles in Anopheles
Baldet, Thierry, Dabiré, K.R., Diabaté, Abdoulaye, Namountougou, Moussa, Ouédraogo, Jean-Bosco, Sawadogo, P., Simard, Frédéric, Toé, K.H.   +7 more
core  

Herbicide-resistant weeds : from research and knowledge to future needs [PDF]

, 2013
Synthetic herbicides have been used globally to control weeds in major field crops. This has imposed a strong selection for any trait that enables plant populations to survive and reproduce in the presence of the herbicide.
Beckie, Hugh John, Busi, Roberto, Gaines, Todd A., Goggin, Danica E., Kaundun, Shiv S., Lacoste, Myrtille, Neve, Paul, Nissen, Scott Jay, Norsworthy, Jason K., Powles, Stephen B., Renton, M., Shaner, Dale L., Tranel, Patrick J., Vila-Aiub, Martin M., Wright, Terry R., Yu, Qin   +15 more
core   +4 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Resistance to Acetyl Coenzyme A Carboxylase (ACCase) Inhibitor in Lolium multiflorum: Effect of Multiple Target-Site Mutations

Agronomy
Italian ryegrass (Lolium multiflorum Lam.) is a persistent weed species that poses significant management challenges in key agricultural crops such as wheat, corn, cotton, and soybean.
Gulab Rangani, Ana Claudia Langaro, Shilpi Agrawal, Reiofeli A. Salas-Perez, Juan Camilo Velásquez, Christopher E. Nelson, Nilda Roma-Burgos   +6 more
doaj   +1 more source

Analysis of the Knockdown Resistance Locus (kdr) in Anopheles stephensi, An. arabiensis, and Culex pipiens s.l. for Insight Into the Evolution of Target-site Pyrethroid Resistance in Eastern Ethiopia [PDF]

, 2022
Tamar E. Carter, Araya Gebresilassie, Shantoy Hansel, Lambodhar Damodaran, Callum Montgomery, Victoria A. Bonnell, Karen López, Daniel Janies, Solomon Yared   +8 more
openalex   +1 more source

Examining the role of protein structural dynamics in drug resistance in Mycobacterium tuberculosis [PDF]

, 2017
Antimicrobial resistance represents a growing global health problem. The emergence of novel resistance mechanisms necessitates the development of alternative approaches to investigate the molecular fundamentals of resistance, leading ultimately to new ...
Adamczyk, Adamczyk, Baiz, Bandaria, Bastian, Best, Chollet, Darden, Deflores, Demirdoven, Dunkelberger, Ganim, Greetham, Hahn, Hamm, Hamm, Hartkoorn, Hess, Hess, Hess, Hochstrasser, Hunt, Husseini, Jansen, Jo, Jorgensen, Kruh, Larsen, Li, Luckner, Merget, Oliveira, Parikh, Perryman, Pronk, Quemard, Rawat, Rozwarski, Shaw, Shaw, Shim, Simpson, Thielges, Torii, Vanommeslaeghe, Verlet, Veyron-Churlet, Veyron-Churlet, Vilcheze, WHO, Zoete   +50 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The blackgrass genome reveals patterns of divergent evolution of non-target site resistance to herbicides [PDF]

, 2021
Lichun Cai, David Comont, Dana R. MacGregor, C. C. Lowe, Roland Beffa, Christopher Saski, Paul Neve   +6 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Dose Splitting Increases Selection for Both Target‐Site and Non‐Target‐Site Fungicide Resistance—A Modelling Analysis

Plant Pathology
ABSTRACT Fungicide resistance management principles recommend that farmers avoid splitting the total dose applied of a fungicidal mode of action (MoA) across multiple applications per season (‘dose splitting’).
Isabel Corkley, Alexey Mikaberidze, Neil Paveley, Frank van den Bosch, Michael W. Shaw, Alice E. Milne   +5 more
openaire   +1 more source