Results 271 to 280 of about 2,083,638 (324)

Novel target sites in bacteria for overcoming antibiotic resistance

Advanced Drug Delivery Reviews, 2005
Resistance to marketed antibiotics continues to increase. During the last 10 years some 200 bacterial genome sequences have become available, giving rise to expectations that genomics would provide a plethora of novel targets and hence a flood of new therapeutic agents.
Michael T, Black, John, Hodgson
openaire   +2 more sources

Confirmation and Characterization of Non–Target Site Resistance to Fomesafen in Palmer Amaranth (Amaranthus palmeri)

Weed science, 2018
Palmer amaranth (Amaranthus palmeri S. Watson), a dioecious summer annual species, is one of the most troublesome weeds in U.S. cropping systems. The evolution of resistance to protoporphyrinogen oxidase inhibitors in A. palmeri biotypes is a major cause
V. Varanasi, Chad B. Brabham, J. Norsworthy   +2 more
semanticscholar   +1 more source

Bacterial resistance to antibiotics: Modified target sites

Advanced Drug Delivery Reviews, 2005
Alteration in the target sites of antibiotics is a common mechanism of resistance. Examples of clinical strains showing resistance can be found for every class of antibiotic, regardless of the mechanism of action. Target site changes often result from spontaneous mutation of a bacterial gene on the chromosome and selection in the presence of the ...
openaire   +2 more sources

Target and non-target site mechanisms of fungicide resistance and their implications for the management of crop pathogens.

Pest Management Science, 2023
BACKGROUND Fungicides are indispensable for high-quality crops, but the rapid emergence and evolution of fungicide resistance have become the most important issues in modern agriculture.
A. Dorigan, Silvino Intra Moreira, Sarah S. C. Guimarães, Valter Cruz-Magalhães, E. Alves   +4 more
semanticscholar   +1 more source

Mapping cryptic binding sites of drug targets to overcome drug resistance

Drug Resistance Updates, 2023
The emergence of drug resistance is a primary obstacle for successful chemotherapy. Drugs that target cryptic binding sites (CBSs) represent a novel strategy for overcoming drug resistance. In this short communication, we explain and discuss how the discovery of CBSs and their inhibitors can overcome drug resistance.
Yang-Yang, Gao, Wei-Cheng, Yang, Charles R, Ashby, Ge-Fei, Hao   +3 more
openaire   +2 more sources

Target-Site Resistance to Cyhalofop-Butyl in Bearded Sprangletop (Diplachne fusca) from China

Weed science, 2019
Bearded sprangletop [Diplachne fusca (L.) P. Beauv. ex Roem. & Schult. ssp. fascicularis (Lam.) P. M. Peterson & N. Snow] is a noxious annual grass weed of paddy fields, distributed in coastal regions of the Jiangsu and Hebei provinces in China ...
Shuzhong Yuan, Y. Di, Yueyang Chen, Yongrui Chen, Jingxuan Cai, Wei Deng   +5 more
semanticscholar   +1 more source

Target-Site and Metabolic Resistance Mechanisms to Penoxsulam in Late Watergrass (Echinochloa phyllopogon) in China.

Journal of Agricultural and Food Chemistry, 2023
Echinochloa phyllopogon, a malignant weed in Northeast China's paddy fields, is currently presenting escalating resistance concerns. Our study centered on the HJHL-715 E. phyllopogon population, which showed heightened resistance to penoxsulam, through a
Haitao Gao, Jiaxing Yu, Jinyi Chen, Hao Wang, Shaoqi Liang, Zhike Feng, Yucheng Gu, Liyao Dong   +7 more
semanticscholar   +1 more source

Non-target Site Mechanisms of Resistance to Herbicides

Critical Reviews in Plant Sciences, 2017
ABSTRACTEvolution of resistance in weeds to herbicides is threatening world agricultural production. Weed management has become more complicated with the development of non-target site resistance (NTSR) to herbicides in weeds. The NTSR mechanisms can be caused by herbicide metabolism, altered patterns of translocation, and herbicide absorption ...
Hossein Ghanizadeh, Kerry C. Harrington
openaire   +1 more source

Target-Site Resistance Mechanisms to Tribenuron-Methyl and Cross-Resistance Patterns to ALS-Inhibiting Herbicides of Catchweed Bedstraw (Galium aparine) with Different ALS Mutations

Weed science, 2018
Catchweed bedstraw (Galium aparine L.) is a problematic dicot weed that occurs in major winter wheat (Triticum aestivum L.) fields in China. Tribenuron-methyl has been widely used to control broadleaf weeds since 1988 in China.
Wei Deng, Y. Di, Jingxuan Cai, Yueyang Chen, Shuzhong Yuan   +4 more
semanticscholar   +1 more source

Investigating target-site resistance mechanism to the PPO-inhibiting herbicide fomesafen in waterhemp and interspecific hybridization of Amaranthus species using next generation sequencing.

Pest Management Science, 2019
BACKGROUND Waterhemp (Amaranthus tuberculatus (Moq.) J. D. Sauer) is one of the most pernicious weeds in cropping systems of the USA due to its evolved resistance against several herbicide sites-of-action, including protoporphyrinogen oxidase inhibitors (
Haozhen Nie, Brent Mansfield, Nick T. Harre, Julie M. Young, N. R. Steppig, B. Young   +5 more
semanticscholar   +1 more source