Results 71 to 80 of about 2,083,638 (324)
Engineered single nucleotide polymorphisms in the mosquito MEK docking site alter Plasmodium berghei development in Anopheles gambiae. [PDF]
, 2014 BackgroundSusceptibility to Plasmodium infection in Anopheles gambiae has been proposed to result from naturally occurring polymorphisms that alter the strength of endogenous innate defenses.
Anishchenko, Michael +5 more
core +3 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Reliability analysis of a glulam beam [PDF]
, 2007 The present case study is an example of the use of reliability analysis to asses the failure probability of a tapered glulam beam. This beam is part of a true structure built for a super market in the town of Kokemaki in Finland. The reliability analysis
Schnabl, Simon +2 more
core +2 more sources
Non-Target Site Mechanisms of Fungicide Resistance in Crop Pathogens: A Review
Microorganisms, 2021 The rapid emergence of resistance in plant pathogens to the limited number of chemical classes of fungicides challenges sustainability and profitability of crop production worldwide.
Mengjun Hu, Shuning Chen
semanticscholar +1 more source
Insecticide resistance resulting from an absence of target-site gene product [PDF]
Proceedings of the National Academy of Sciences, 1998 Genetic changes in insects that lead to insecticide resistance include point mutations and up-regulation/amplification of detoxification genes. Here, we report a third mechanism, resistance caused by an absence of gene product. Mutations of the Methoprene-tolerant ( Met ) gene of ...
T G, Wilson, M, Ashok
openaire +2 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Julius-Kühn-Archiv, 2012 Neighboring fields in three local areas of southern Germany have been investigated for the infestation level and herbicide resistance structure of black-grass (Alopecurus myosuroides Huds.).
Hess, Martin +5 more
doaj +1 more source
ACCase-inhibiting herbicides: mechanism of action, resistance evolution and stewardship
Scientia Agricola, 2020 Herbicides play an important role in preventing crop yield losses due to both their weed interference ability and their capacity for increasing soil conservation in no-till systems.
Hudson Kagueyama Takano +4 more
doaj +1 more source
Does insecticide resistance contribute to heterogeneities in malaria transmission in The Gambia? [PDF]
, 2016 BACKGROUND: Malaria hotspots, areas with consistently higher than average transmission, may become increasingly common as malaria declines. This phenomenon, currently observed in The Gambia, may be caused by several factors, including some related to the
Crombe, Florence +8 more
core +4 more sources