Results 81 to 90 of about 1,394,726 (329)

Role of a novel I1781T mutation and other mechanisms in conferring resistance to acetyl-CoA carboxylase inhibiting herbicides in a black-grass population. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Knowledge of the mechanisms of herbicide resistance is important for designing long term sustainable weed management strategies. Here, we have used an integrated biology and molecular approach to investigate the mechanisms of resistance to ...
Shiv Shankhar Kaundun   +3 more
doaj   +1 more source

Predicting Resistance by Mutagenesis: Lessons from 45 Years of MBC Resistance [PDF]

open access: yes, 2016
When a new fungicide class is introduced, it is useful to anticipate the resistance risk in advance, attempting to predict both risk level and potential mechanisms.
Bart A. Fraaije, Nichola J. Hawkins
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

"Non-Target-Site" resistance mechanisms of "Papaver rhoeas" L. biotypes with multiple resistance [PDF]

open access: yes, 2015
Hasta el momento en España no se han desarrollado estudios a fin de evaluar los mecanismos de resistencia “Non-Target-Site” en “Papaver rhoeas”. Tras constatar la resistencia múltiple de los biotipos empleados en este ensayo, los resultados de absorción ...
Menéndez, J.   +3 more
core  

Reliability analysis of a glulam beam [PDF]

open access: yes, 2007
The present case study is an example of the use of reliability analysis to asses the failure probability of a tapered glulam beam. This beam is part of a true structure built for a super market in the town of Kokemaki in Finland. The reliability analysis
Schnabl, Simon   +2 more
core   +2 more sources

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Genetic diversity and identification of symbiotic community of Q Bemisia tabaci from Mediterranean countries [PDF]

open access: yes, 2011
Introduction: We investigated a) the genetic diversity and population structure, b) the secondary symbiotic bacterial community and c) the frequencies of target site mutations conferring resistance to pyrethroids and organophospates in Q Bemisia tabaci ...
Bourtzis, Kostas   +5 more
core  

L925I mutation in the Para-type sodium channel is associated with pyrethroid resistance in Triatoma infestans from the Gran Chaco region [PDF]

open access: yes, 2014
Background: Chagas' disease is an important public health concern in Latin America. Despite intensive vector control efforts using pyrethroid insecticides, the elimination of Triatoma infestans has failed in the Gran Chaco, an ecoregion that extends over
Capriotti, Natalia   +3 more
core   +3 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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