Results 101 to 110 of about 2,565,028 (307)
Skeletal Muscle, 2018 Following publication of the original article [1], the authors flagged that there is a discrepancy with the Availability of data and materials statement on page 12 of the article.
Andrew N. Billin +18 more
doaj +1 more source
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. [PDF]
, 2010 Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here we identify the triglyceride-synthesizing enzyme diacylglycerol acyltransferase-1 (DGAT1) as a key host factor for HCV infection.
Carpentier, Arnaud +7 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee +9 more
wiley +1 more source
Frontiers in Cardiovascular MedicineBackgroundPatients with hypertrophic cardiomyopathy (HCM) often experience exercise intolerance. However, the primary determinants of exercise capacity in patients with HCM remain unclear.ObjectivesThis study aimed to evaluate exercise intolerance in ...
Mengdi Yu +14 more
doaj +1 more source
HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury
Skeletal Muscle, 2018 Background In muscular dystrophy and old age, skeletal muscle repair is compromised leading to fibrosis and fatty tissue accumulation. Therefore, therapies that protect skeletal muscle or enhance repair would be valuable medical treatments.
Andrew N. Billin +18 more
doaj +1 more source
Targeting STAT3 in Cancer with Nucleotide Therapeutics. [PDF]
, 2019 Signal transducer and activator of transcription 3 (STAT3) plays a critical role in promoting the proliferation and survival of tumor cells. As a ubiquitously-expressed transcription factor, STAT3 has commonly been considered an "undruggable" target for ...
Grandis, Jennifer R +3 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song +15 more
wiley +1 more source
The role of the individual in the coming era of process-based therapy [PDF]
, 2018 For decades the development of evidence-based therapy has been based on experimental tests of protocols designed to impact psychiatric syndromes. As this paradigm weakens, a more process-based therapy approach is rising in its place, focused on how to ...
Carpenter, Joseph K. +6 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian +7 more
wiley +1 more source
Frontiers in Cardiovascular MedicineBackgroundEssential hypertension (EH) in young and middle-aged adults is a major risk factor for cardiovascular morbidity, yet the detailed molecular mechanisms underlying this condition have not been fully understood.
Xiu-Long Niu +22 more
doaj +1 more source