Results 21 to 30 of about 3,752,482 (246)

Insights into molecular pathways for targeted therapeutics in acute leukaemia

Swiss Medical Weekly, 2010
Despite the development of modern chemotherapeutic regimens, acute leukaemia remains incurable in the majority of adult patients and potential cure is associated with considerable side effects. Clinical and experimental research of the last two decades
V Stavropoulou, L Brault, J Schwaller
doaj   +1 more source

Sotorasib – an inhibitor of KRAS p.G12c mutation in advanced non-small cell carcinoma: A narrative drug review

Cancer Research, Statistics, and Treatment, 2021
The KRAS p.G12C mutation occurs in seen in 13% of non-small cell lung cancers (NSCLCs) and in approximately 1%–3% of colorectal and other cancers. Until the last decade, there were no approved therapies for targeting the KRAS mutation, but recently ...
Amit Kumar Agrawal, Ramya Pragya, Amit Choudhary, Anuj Gupta, Kuraparthy Sambasivaiah, Bal Krishna Mishra, Satvik Khaddar, Akhil Kapoor   +7 more
doaj   +1 more source

Phase-Shift, Targeted Nanoparticles for Ultrasound Molecular Imaging by Low Intensity Focused Ultrasound Irradiation [Retraction]

International Journal of Nanomedicine, 2022
Li M, Luo H, Zhang W, et al. Int J Nanomedicine. 2018;13:3907–3920. The Editor and Publisher of International Journal of Nanomedicine wish to retract the published article.
Li M, Luo H, Zhang W, He K, Chen Y, Liu J, Chen J, Wang D, Hao L, Ran H, Zheng Y, Wang Z, Li P   +12 more
doaj  

Advances in targeting tumor microenvironment for immunotherapy

Frontiers in Immunology
The tumor microenvironment (TME) provides essential conditions for the occurrence, invasion, and spread of cancer cells. Initial research has uncovered immunosuppressive properties of the TME, which include low oxygen levels (hypoxia), acidic conditions (
Lugang Wang, Lugang Wang, Liubo Zhang, Zhen Zhang, Peng Wu, Yi Zhang, Yi Zhang, Yi Zhang, Yi Zhang, Yi Zhang, Yi Zhang, Xinfeng Chen, Xinfeng Chen   +12 more
doaj   +1 more source

Technical training of highly skilled hockey players on the grass in the Context of Model-purpose approach [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2013
The possibilities of improving sportsmanship hockey on grass-based modeling-based approach. The aim is to study the dynamics of technical preparedness of highly qualified hockey players on grass under the influence of experimental summer system of ...
Perepelytsya O.A.
doaj   +1 more source

Antitumor activity of the tea polyphenol epigallocatechin-3-gallate encapsulated in targeted vesicles after intravenous administration [PDF]

, 2013
The therapeutic potential of epigallocatechin gallate, a green tea polyphenol with anti-cancer properties, is limited by its inability to specifically reach tumors following intravenous administration.
Dufès, Christine, Lemarié, Fanny, Norris, Greg, McConnell, Gail, Chang, Chun Wai, Amor, Rumelo, Tetley, Laurence, Blatchford, David   +7 more
core   +4 more sources

Mast cell stabilizers: from pathogenic roles to targeting therapies

Frontiers in Immunology
Mast cells (MCs) are bone-marrow-derived haematopoietic cells that are widely distributed in human tissues. When activated, they will release tryptase, histamine and other mediators that play major roles in a diverse array of diseases/disorders ...
Mengda Cao, Yao Gao
doaj   +1 more source

Phase-Shift, Targeted Nanoparticles for Ultrasound Molecular Imaging by Low Intensity Focused Ultrasound Irradiation [Corrigendum]

International Journal of Nanomedicine, 2020
Li M, Luo H, Zhang W, et al. Int J Nanomedicine. 2018;13:3907–3920. The authors have advised that they covered up some larger-sized particles and impurities to enhance the aesthetic of the image shown for Figure 4A, on page 3913 ...
Li M, Luo H, Zhang W, He K, Chen Y, Liu J, Chen J, Wang D, Hao L, Ran H, Zheng Y, Wang Z, Li P   +12 more
doaj  

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Targeted Renal Biopsy: Predictors on Imaging

The Arab Journal of Interventional Radiology, 2022
Objectives The renal nephrometry score uses imaging characteristics such as lesion diameter, location, and proximity to hilar vessels to categorize renal masses by complexity for preoperative planning.
Janki Trivedi, Arpit Talwar, Ahmed Nada, Simon Li, Adele Lee, Tom R. Sutherland   +5 more
doaj   +1 more source