Results 311 to 320 of about 7,670,364 (343)

Targeted metabolomics reveals PFKFB3 as a key target for elemene-mediated inhibition of glycolysis in prostate cancer cells.

Phytomedicine, 2023
BACKGROUND Elemene, an active anticancer extract derived from Curcuma wenyujin, has well-documented anticarcinogenic properties. Nevertheless, the role of elemene in prostate cancer (PCa) and its underlying molecular mechanism remain elusive.
Xue-Man Dong, Lin Chen, Pu Wu, Long-Hui Cheng, Yu Wang, Youjian Yang, Yongwei Zhang, Wei-Yang Tang, Tian Xie, Jian‐Liang Zhou   +9 more
semanticscholar   +1 more source

Widely Targeted Metabolomics Analysis of Dendrobium officinale at Different Altitudes

Chemistry and Biodiversity, 2023
In order to investigate the differences in the chemical composition of Dendrobium officinale at different altitudes, we collected Dendrobium officinale from different altitudes in Guizhou Province, China, and firstly determined its polysaccharide content
Xiaohuan Jia, Fa-Ming Wu, An-Jing Lu, Dao-Peng Tan, Qianru Zhang, Yu-Qi He, Lin Qin   +6 more
semanticscholar   +1 more source

A large-scale, targeted metabolomics method for the analysis and quantification of metabolites in human plasma via liquid chromatography-mass spectrometry.

Analytica Chimica Acta, 2023
Metabolomics is the study of small molecules, primarily metabolites, that are produced during metabolic processes. Analysis of the composition of an organism's metabolome can yield useful information about an individual's health status at any given time.
Teresa S. McMillen, Andrew Leslie, K. Chisholm, Susanne Penny, Jeff Gallant, Alejandro M. Cohen, A. Drucker, James P. Fawcett, Devanand M. Pinto   +8 more
semanticscholar   +1 more source

Comprehensive investigation on non-volatile and volatile metabolites in four types of green teas obtained from the same tea cultivar of Longjing 43 (Camellia sinensis var. sinensis) using the widely targeted metabolomics.

Food Chemistry, 2022
In this study, we produced roasted, baked, steamed, and sun-dried green tea products using the same batch of fresh tea leaves (FTL) of Longjing 43 (Camellia sinensis var.
Yali Shi, Yin Zhu, Wanjun Ma, Jiang Shi, Qun-Hua Peng, Zhi Lin, Hai-Peng Lv   +6 more
semanticscholar   +1 more source

Widely targeted metabolomics analysis reveals new biomarkers and mechanistic insights on chestnut (Castanea mollissima Bl.) calcification process.

Food Research International, 2021
Chestnut calcification is a quality deterioration due to fast water loss, which has been of deep concern for chestnut quality control because its mechanism is unclear.
Jiaqi Xiao, Cai-Qin Gu, Shan He, Dongxue Zhu, Yu-Kai Huang, Qiqin Zhou   +5 more
semanticscholar   +1 more source

Untargeted and Targeted Metabolomics Profiling of Muscle Reveals Enhanced Meat Quality in Artificial Pasture Grazing Tan Lambs via Rescheduling the Rumen Bacterial Community.

Journal of Agricultural and Food Chemistry, 2021
Tan is a local fat-tail sheep that is famous for its great eating quality but with little attention to its meat metabolome. The aim of this study was to investigate Tan-lamb meat metabolome as well as the key rumen bacteria related to the beneficial ...
Bing Wang, Yuejun Wang, Shuxian Zuo, Sijia Peng, Zhanjun Wang, Ying-Jun Zhang, Hai-Ling Luo   +6 more
semanticscholar   +1 more source

Widely targeted metabolomics analysis reveals the effect of fermentation on the chemical composition of bee pollen.

Food Chemistry, 2021
Microbial fermentation can break the bee pollen wall. However, the global profiling of bee pollen metabolites under fermentation remains unclear. This study aims to comprehensively elucidate the changes in the composition of bee pollen after microbial ...
Huifang Zhang, Qun Lu, R. Liu
semanticscholar   +1 more source

Analysis of volatile metabolite variations in strip green tea during processing and effect of rubbing degree using untargeted and targeted metabolomics.

Food Research International, 2022
Strip green tea (SGT) is widely distributed in China owing to its unique appearance and aroma but the evolution and formation mechanisms of volatile metabolites (VMs) during SGT processing, and especially in the unique process of rubbing, remain unclear.
Wen Ouyang, Ya-Ya Yu, Hua-Jie Wang, Yong-Wen Jiang, J. Hua, Jingming Ning, Hai-Bo Yuan   +6 more
semanticscholar   +1 more source

Targeted Metabolomics for Biomarker Discovery

Angewandte Chemie - International Edition, 2010
Metabolomics is a truly interdisciplinary field of science, which combines analytical chemistry, platform technology, mass spectrometry, and NMR spectroscopy with sophisticated data analysis.
Matthias Kohl, Yuqin Wang, William J Griffiths   +2 more
exaly   +2 more sources

Metabolite identification in fresh wheat grains of different colors and the influence of heat processing on metabolites via targeted and non-targeted metabolomics.

Food Research International, 2022
Phenolic antioxidants are phytochemical components in wheat grains that provide a variety of potential health benefits. The metabolites and antioxidant activity of fresh, mature, and heat-treated, wheat grains with black, blue, purple, and white grain ...
Jian-Chao Feng, Bei-Ming Xu, Dong-Yun Ma, Zirui Hao, Yuku Jia, Chen-Yang Wang, Lifang Wang   +6 more
semanticscholar   +1 more source