Results 21 to 30 of about 38,995 (207)

Study protocol for a single-centre non-inferior randomised controlled trial on a novel three-dimensional matrix positioning-based cognitive fusion-targeted biopsy and software-based fusion-targeted biopsy for the detection rate of clinically significant prostate cancer in men without a prior biopsy

BMJ Open, 2021
Introduction The classical pathway for diagnosing prostate cancer is systematic 12-core biopsy under the guidance of transrectal ultrasound, which tends to underdiagnose the clinically significant tumour and overdiagnose the insignificant disease ...
Haifeng Wang, Biming He, Rongbing Li, Dongyang Li, Liqun Huang, Xiaofei Wen, Guosheng Yang   +6 more
doaj   +1 more source

Transperineal Prostate Biopsy Targeted by Magnetic Resonance Imaging Cognitive Fusion

Diagnostics, 2023
Prostate cancer is among the most frequently diagnosed cancers and a leading cause of cancer-related death in men. Currently, the most reliable and widely used imaging test for prostate cancer diagnosis is multiparametric pelvic magnetic resonance ...
Petru Octavian Drăgoescu, Andrei Ioan Drocaș, Alice Nicoleta Drăgoescu, Vlad Pădureanu, Andrei Pănuș, Andreea Doriana Stănculescu, Mihai Alexandru Radu, Lucian Mihai Florescu, Ioana Andreea Gheonea, Cecil Mirea, George Mitroi   +10 more
doaj   +1 more source

Outcomes of combination MRI-targeted and transperineal template biopsy in restaging low-risk prostate cancer for active surveillance

Asian Journal of Urology, 2018
Objective: Active surveillance (AS) offers a strategy to reduce overtreatment and now is a widely accepted treatment option for low-risk prostate cancer.
Kenneth Chen, Kae Jack Tay, Yan Mee Law, Hakan Aydin, Henry Ho, Christopher Cheng, John Shyi Peng Yuen   +6 more
doaj   +1 more source

Multiparametric Prostate MRI in Biopsy-Naïve Men: A Prospective Evaluation of Performance and Biopsy Strategies

Frontiers in Oncology, 2021
ObjectivesThis study aims to prospectively estimate the diagnostic performance of multiparametric prostate MRI (mpMRI) and compare the detection rates of prostate cancer using cognitive targeted transrectal ultrasound (TRUS) guided biopsies, targeted MR ...
Brage Krüger-Stokke, Brage Krüger-Stokke, Helena Bertilsson, Helena Bertilsson, Sverre Langørgen, Torill Anita Eidhammer Sjøbakk, Tone Frost Bathen, Tone Frost Bathen, Kirsten Margrete Selnæs, Kirsten Margrete Selnæs   +9 more
doaj   +1 more source

Three-dimensional printing technique assisted cognitive fusion in targeted prostate biopsy

Asian Journal of Urology, 2015
Objective: To explore the effect of 3-dimensional (3D) printing-assisted cognitive fusion on improvement of the positive rate in prostate biopsy.
Yan Wang, Xu Gao, Qingsong Yang, Haifeng Wang, Ting Shi, Yifan Chang, Chuanliang Xu, Yinghao Sun   +7 more
doaj   +1 more source

Multiparametric MRI fusion-guided prostate biopsy in biopsy naive patients: Preliminary results from 80 patients

Urology Research and Practice, 2019
Objective: The aim of this prospective study was to evaluate the early results of transrectal prostate biopsies performed under the guidance of multiparametric prostate magnetic resonance imaging (mpMRI) in biopsy naive patients.
Gökhan Sönmez, Şevket Tolga Tombul, Hakan İmamoğlu, Hülya Akgün, Abdullah Demirtaş, Atila Tatlışen   +5 more
doaj   +1 more source

Cancer detection rate of prebiopsy MRI with subsequent systematic and targeted biopsy are superior to non-targeting systematic biopsy without MRI in biopsy naïve patients: a retrospective cohort study

BMC Urology, 2018
Background To determine whether prebiopsy multiparametric magnetic resonance imaging (mpMRI) with subsequent systematic plus targeted biopsies for suspicious lesions improve prostate cancer detection compared with standard non-targeting systematic ...
Satoshi Washino, Shigeru Kobayashi, Tomohisa Okochi, Tomohiro Kameda, Tsuzumi Konoshi, Tomoaki Miyagawa, Tatsuya Takayama, Tatsuo Morita   +7 more
doaj   +1 more source

Multiparametric magnetic resonance imaging-transrectal ultrasound fusion biopsies increase the rate of cancer detection in populations with a low incidence of prostate cancer [PDF]

Investigative and Clinical Urology, 2019
Purpose: To prospectively evaluate the diagnostic yield of multiparametric magnetic resonance imaging (mpMRI)-fusion, transrectal ultrasound (TRUS)-guided prostate biopsies for detection of prostate cancer in an Asian population with a low incidence of ...
Rohit Kaushal, Chandan J. Das, Prabhjot Singh, Prem Nath Dogra, Rajeev Kumar   +4 more
doaj   +1 more source

Multiparametric MRI Fusion-Guided Prostate Biopsy for Detection of Clinically Significant Prostate Cancer Eliminates the Systemic Prostate Biopsy

Applied Sciences, 2022
The primary objective of this study was to demonstrate the high accuracy of multiparametric magnetic resonance imaging and ultrasound fusion (mpMRI/US)-guided targeted prostate biopsy for the detection of clinically significant prostate cancer (PCa) and ...
Augustinas Matulevičius, Arnas Bakavičius, Albertas Ulys, Mantas Trakymas, Jurgita Ušinskienė, Ieva Naruševičiūtė, Rasa Sabaliauskaitė, Kristina Žukauskaitė, Sonata Jarmalaitė, Feliksas Jankevičius   +9 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source