Results 111 to 120 of about 5,184,182 (156)

Bridging E3 Ligase Binding and Targeted Degradation Through Fluorescence Polarization. [PDF]

Int J Mol Sci
González-Pico L, Camino T, Ortigueira S, Prieto-Díaz R, Sotelo E, Majellaro M.   +5 more
europepmc   +1 more source

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review). [PDF]

Mol Med Rep
Bai Y, Ma D, Yang X, Wang M.
europepmc   +1 more source

From Epigenetic Regulation to Protein Degradation: Emerging Strategies for Anti-Infective Drug Discovery. [PDF]

Int J Mol Sci
Bonjorno AF, Boreski D, Rodriguez Gini AL, Souza Tada da Cunha P, Moura JA, Chin CM, Benito Scarim C, Dos Santos JL.   +7 more
europepmc   +1 more source

Design, Synthesis, Biological Studies and Putative Binding Mode of Novel Benzotriazolothalidomide Derivatives as Cereblon Ligands. [PDF]

Chem Biol Drug Des
Ganguly P, Kundu M, Sarkar T, Dcosta G, Banerjee K, Banerjee R, Hajra AK, Sahabuddin S, Basu S, Das A, Das S, Barik R, Ali MA.   +12 more
europepmc   +1 more source

Harnessing FBXO31 with Terminal Amide-Functionalized Molecules for Targeted Protein Degradation. [PDF]

J Am Chem Soc
Zhang C, Jin X, Zhou C, Jenkins MJ, Riha IA, Zhang X.   +5 more
europepmc   +1 more source

Exploring Novel E3 Ligases and Neosubstrates for Molecular Glue Degraders and Therapeutic Applications in Cancer. [PDF]

Oncol Res
Jang JH, Kim JY, Lee TJ.
europepmc   +1 more source

Ubiquitin E3 ligase activity in TRIpartite Motif (TRIM) family proteins. [PDF]

Biochem Soc Trans
Dudley-Fraser J, Rittinger K.
europepmc   +1 more source

Targeted degradation of c-Myc through the midnolin-proteasome pathway. [PDF]

Proc Natl Acad Sci U S A
Zhao J, Wu H, Yu H, Li C, Mao Y, Yuan H, Li S.   +6 more
europepmc   +1 more source

Research progress and future perspectives in proteolysis-targeting chimeras. [PDF]

Front Pharmacol
Wu N, Xu Z, Dai S, Wang Q.
europepmc   +1 more source

Ultrahigh-Throughput Liquid Chromatography with Tandem Mass Spectrometry Method for Targeted Protein Degradation Compound Screening Using the Orbitrap Astral Mass Spectrometer. [PDF]

J Proteome Res
Lin H, Yang YY, Maity S, Sun Q, Wang J.
europepmc   +1 more source