Results 121 to 130 of about 5,184,182 (156)

Identification of Clofibric Acid as a Synoviolin (SYVN1) Ligand for Proteolysis-Targeting Chimera (PROTAC) Development. [PDF]

ACS Med Chem Lett
Warren J, Munakala A, Zientek KD, Kim K, Wilmarth PA, Reddy AP, Li BX, Xiao X.   +7 more
europepmc   +1 more source

Advancing targeted protein degradation: pLIRTAC's role in glioma and CAR-T cell therapy. [PDF]

Autophagy
Lei K, Li Y, Zhou Z, Li J, Huang L, Liu W, Huang K, Zhu X.   +7 more
europepmc   +1 more source

Dual PROTACs Versus Dual Inhibitors in Oncology: A Medicinal Chemistry and Linker Design Perspective. [PDF]

Pharmaceuticals (Basel)
Bisi N, Hamze A.
europepmc   +1 more source

Redirecting TRIM21 with TRIMTACs for the targeted degradation of multimeric proteins. [PDF]

FEBS J
Scemama de Gialluly MA, Adams DJ.
europepmc   +1 more source

Discovery of PROTACs recruiting the E3 ligase CHIP. [PDF]

RSC Chem Biol
Masuda-Ozawa T, Tomoshige S, Hayakawa E, Sato S, Ohgane K, Ohtake F, Ishikawa M.   +6 more
europepmc   +1 more source

Mechanisms and Design Principles of Proteolysis-Targeting Chimeras and Their Emerging Applications. [PDF]

ACS Pharmacol Transl Sci
Knoll N, Neamati N, Üren A.
europepmc   +1 more source

Bellerophon: An Automated Tool for PROTAC Decomposition. [PDF]

ACS Med Chem Lett
Apprato G, Bertola M, Locatelli A, Caron G, Mauri A, Ermondi G.   +5 more
europepmc   +1 more source

A real-time FRET ubiquitin transfer assay for quantitative characterization of ternary complexes in targeted protein degradation. [PDF]

Cell Rep Methods
Yu CH, Dougherty V, Lv D, Ebadi P, Dubey S, Nayak D, Nayak A, Zhou D, Olsen SK, Ivanov DN.   +9 more
europepmc   +1 more source

LCK-targeting molecular glues overcome resistance to inhibitor-based therapy in T-cell acute lymphoblastic leukemia.

Blood
Yoshimura S, Actis M, Seffernick JT, McGrath L, Jarusiewicz JA, Aggarwal A, Li A, Li Y, Lee D, Yang L, Mayasundari A, Rankovic Z, Fischer M, Nishiguchi G, Yang JJ.   +14 more
europepmc   +1 more source