Results 101 to 110 of about 13,805 (198)

Artificial Intelligence and Prostate–Breast Cancer Biology: Recent Advances in Treatments and Perspectives — A Comprehensive Review

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims The therapeutic limitations of conventional cancer treatment currently deployed are driving the development and creation of new nano‐drugs. Prostate cancer (PCa) is a prevalent clinical problem in older men with a significant global incidence, with 1.5 million cases reported in 2022.
Russell B. O. Ouma, Silas M. Ngari, Joshua K. Kibet   +2 more
wiley   +1 more source

Synthesis, Radiochemical Characterization, and Biodistribution of a 188Re Analogue of [131I]mIBG in a Neuroblastoma Xenograft Model

Journal of Labelled Compounds and Radiopharmaceuticals, Volume 69, Issue 3, March 2026.
A 188Re analogue of [131I]mIBG was synthesized in moderate yields using 188Re‐4 + 1 chemistry. In vitro studies using SK‐N‐SH neuroblastoma cell lines demonstrated that the compound exhibited affinity for norepinephrine transporters expressed on these cancer cells.
Navin Sakhare, Dheeraj Kumar, Soumen Das, Arpit Mitra, Shubhangi Mirapurkar, G. Rani, M. Sheela, Viju Chirayil, Bhabani Mohanty, Anupam Mathur, Madhava B. Mallia, Pradip Chaudhari   +11 more
wiley   +1 more source

Chromatin Accessibility in Cancer: Biological Functions, Mechanisms, Therapeutic Potential, and Future Directions

MedComm, Volume 7, Issue 3, March 2026.
Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia, Min Jiang, Yefei Huang, Kun Ding, Yansu Chen   +4 more
wiley   +1 more source

Revisiting the segmentation threshold for Lu‐177 SPECT

Medical Physics, Volume 53, Issue 3, March 2026.
Abstract Background The mostly used threshold‐based segmentation method for SPECT, i.e., 42% of the maximum intensity, was derived from 99mTc and may not be directly applicable to 177Lu. Purpose This study aims to revisit the optimal segmentation threshold for 177Lu SPECT.
Yibin Liu, Jian Yang, Peng Wang, Yingwei Wang, Yue Chen, Greta S. P. Mok   +5 more
wiley   +1 more source

Bismuth Bicycles

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
Discovery, evolution and potential future applications of bismuth bicycle molecules—a novel class of therapeutics with unique properties. ABSTRACT Bicyclic peptides are emerging as next generation therapeutics by combining the affinity and specificity of antibodies with the synthetic convenience of small molecules.
Saan Voss, Amin Sagar, Arnaud Tiberghien, Richard J. L. Hughes, Liuhong Chen, Inmaculada Rioja, Mark Frigerio, Michael J. Skynner, David R. Spring   +8 more
wiley   +1 more source

Precision strikes: PSMA-targeted radionuclide therapy in prostate cancer - a narrative review. [PDF]

Front Oncol, 2023
Szponar P, Petrasz P, Brzeźniakiewicz-Janus K, Drewa T, Zorga P, Adamowicz J.   +5 more
europepmc   +1 more source

Human Meningiomas Reveal No Evidence of Neuroendocrine Differentiation

APMIS, Volume 134, Issue 3, March 2026.
ABSTRACT Meningiomas are heterogeneous tumors and studies suggest that meningiomas might be part of MEN1 syndrome. The tumors express somatostatin receptors (SSTRs) comparable to that seen in neuroendocrine neoplasms. We aimed to explore neuroendocrine differentiation in meningiomas by investigating the following neuroendocrine markers: neural cell ...
Sofie Eline Tollefsen, Anders Hagen Jarmund, Ole Solheim, Ida Kaalhus Nordahl, Thi My Linh Hoang, Anette H. Skjervold, Patricia Mjønes, Sverre Helge Torp   +7 more
wiley   +1 more source

Targeted radionuclide therapy [PDF]

Journal of Labelled Compounds and Radiopharmaceuticals, 2007
openaire   +1 more source

Fibroblast activation protein (FAP)-targeted radionuclide therapy: which ligand is the best? [PDF]

Eur J Nucl Med Mol Imaging, 2023
Chakravarty R, Song W, Chakraborty S, Cai W.   +3 more
europepmc   +1 more source

Gadolinium-Based Nanoparticles Sensitize Ovarian Peritoneal Carcinomatosis to Targeted Radionuclide Therapy. [PDF]

J Nucl Med, 2023
Garcia-Prada CD, Carmes L, Atis S, Parach A, Bertolet A, Jarlier M, Poty S, Garcia DS, Shin WG, Du Manoir S, Schuemann J, Tillement O, Lux F, Constanzo J, Pouget JP.   +14 more
europepmc   +1 more source