Results 101 to 110 of about 26,593 (244)

Recent Progress of Functionalized PSMA in Radionuclide Targeted Therapy for Prostate Cancer

Zhongliu Fangzhi Yanjiu, 2020
Prostate cancer (PCa) is the most common malignant tumor in the male reproductive system. Prostate specific membrane antigen (PSMA) is an effective target for the diagnosis and treatment of prostate cancer.
REN Ya'nan, LIU Teli, LI Dapeng, LI Hui, DING Jin, ZHU Hua, YANG Zhi   +6 more
doaj   +1 more source

Functionalized NaA Nanozeolites Labeled with 224,225Ra for Targeted Alpha Therapy [PDF]

, 2013
The 223Ra, 224Ra, and 225Ra radioisotopes exhibit very attractive nuclear properties for application in radionuclide therapy. Unfortunately the lack of appropriate bifunctional ligand for radium is the reason why these radionuclides have not found ...
AGATA Piotrowska, BILEWICZ Aleksander, BRUCHERTSEIFER Frank, EDYTA Leszczuk, MORGENSTERN Alfred   +4 more
core   +1 more source

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source

Combination Strategies and Targeted Radionuclide Therapies

Seminars in Nuclear Medicine
Combination models utilising treatments from two or more therapeutic classes are well established in cancer care. In the new era of theranostic (theragnostic) medicine there is an ongoing need to identify and refine novel combination strategies to optimise multidisciplinary care for conditions commonly encountered in nuclear medicine such as ...
Kerry Jewell, Louise Kostos, Brittany Emmerson, Michael S. Hofman   +3 more
openaire   +3 more sources

Occupational burnout in nuclear medicine technologists working in Australia and New Zealand – results of a multi‐national survey

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 25-33, March 2025.
Occupational burnout is associated with negative feelings about the workplace and is often caused by a high workload and a non‐supportive workplace. It is associated with absenteeism, high turnover of staff and decreased patient care. More than half of the New Zealand participants and three quarters of the Australian participants had moderate levels of
Melissa Shields, Daphne James, Lynne McCormack   +2 more
wiley   +1 more source

Eleven-year experience with the avidin-biotin pretargeting system in glioblastoma: Toxicity, efficacy and survival [PDF]

, 2012
Background: The 3-step avidin-biotin pretargeting approach is applied in patients with recurrent glioblastoma (GBM), using biotinylated anti-tenascin monoclonal antibody as the first step of pretargeting followed by avidin and 90Ybiotin.
Baio, Silvia M., Bartolomei, Mirco, Bodei, Lisa, Broggi, Giovanni, Chinol, Marco, Cremonesi, Marta, De Cicco, Concetta, Grana, Chiara M., Pacifici, Monica, Paganelli, Giovanni, Rocca, Paola A., Severi, Stefano, Tiberini, Simone   +12 more
core   +2 more sources

Targeted Radionuclide Therapy

, 2022
The aim of this work is to improve the current computational dosimetry approaches for in vitro and in vivo TRT treatment in order to correlate microdosimetry with biological effects. The creation of such computational frameworks and the investigation of the radiobiology of dose-response in TRT in cells and in small animals can ultimately lead to a ...
openaire   +1 more source

Molecular theranostics: principles, challenges and controversies

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 156-164, March 2025.
Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley   +1 more source

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, EarlyView.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Lead-212 Radiopharmaceuticals for Receptor-Targeted Radionuclide Therapy [PDF]

Journal of Mazandaran University of Medical Sciences
Receptor-targeted radionuclide therapy (RTRT) combines the power of particle-emitting radionuclides with the receptor-targeting capabilities of biomolecules, including antibodies and peptides.
Solmaz Mojarad-Jabali, Sajjad Molavipordanjani   +1 more
doaj