Results 131 to 140 of about 26,593 (244)

Evaluation and Management of Thyroid Nodules: A Joint Consensus Statement From the British Thyroid Association (BTA), British Association of Endocrine and Thyroid Surgeons (BAETS) and Collaborating Bodies

Clinical Endocrinology, Volume 104, Issue 6, Page 682-692, June 2026.
Ram Moorthy, Saba P. Balasubramanian, Kate Farnell, Mairead Kelly, Gitta Madani, Mufaddal Moonim, Carla Moran, Julia Priestley, Michael Stechman, Emma Watts, Kristien Boelaert   +10 more
wiley   +1 more source

Calcium Channel Blockers Inhibit Pancreatic Neuroendocrine Neoplasms Progression via Cav1.2‐Epigenetic Circuit

Advanced Science, Volume 13, Issue 20, 9 April 2026.
Our study reveals a novel mechanism of a positive regulatory circuit between Cav1.2 and H3K27ac for pancreatic neuroendocrine neoplasms (pNENs) progression. Cav1.2 is identified as a crucial target for promoting disease progression and correlates with malignant behaviors, which are remarkably inhibited by the administration of calcium channel blockers (
Yangyinhui Yu, Qiongcong Xu, Jinzhao Xie, Mingjian Ma, Xitai Huang, Yinhao Shi, Jiawei Zhou, Enliang Zhu, Ziyi Zhao, Ning Zhang, Zhide Liu, Jingyuan Ye, Xiaoyu Yin   +12 more
wiley   +1 more source

Radionuclide-Labeled Biomaterials: A Novel Strategy for Tumor-Targeted Therapy

Biomimetics
This paper presents a comprehensive review of recent advancements in radionuclide-labeled biomaterials for cancer therapy, with a particular focus on the characteristics, production methods, and labeling techniques of α-particle, β-particle, and Auger ...
Shu Zhang, Aiyue Zhang, Xunhao Qi, Zongtai Han, Luqi Song, Jiayu Zhou, Guanglin Wang, Ran Zhu, Jianguo Li   +8 more
doaj   +1 more source

Ultrasound‐Responsive Engineered Bacteria for Targeted Cancer Therapy: Strategies, Mechanisms, and Applications

Advanced Science, Volume 13, Issue 20, 9 April 2026.
This review elucidates URB design strategies, including genetic and physicochemical modifications, while dissecting the synergistic mechanisms governing spatiotemporal control. It further evaluates applications in targeted drug delivery, gene modulation, and immunotherapy, finally offering perspectives on overcoming translational barriers for clinical ...
Xueyao Wang, Wenjing Xu, Yafang Lu, Huaibin Yu, Zhengbao Zha, Xijun Zhang   +5 more
wiley   +1 more source

First Ex-Vivo Validation of a Radioguided Surgery Technique with beta- Radiation

, 2016
Purpose: A radio-guided surgery technique with beta- -emitting radio-tracers was suggested to overcome the effect of the large penetration of gamma radiation.
Bocci, V., Camillocci, E. Solfaroli, Carollo, A., Chiodi, G., Colandrea, M., Collamati, F., Cremonesi, M., Donnarumma, R., Faccini, R., Ferrari, M. E., Ferroli, P., Ghielmetti, F., Grana, C. M., Marafini, M., Morganti, S., Patanè, M., Pedroli, G., Pollo, B., Recchia, L., Russomando, A., Schiariti, M., Terracciano, C. Mancini, Toppi, M., Traini, G.   +23 more
core   +1 more source

Biopharmaceuticals for Cancer Treatment: An Update

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Cancer is one of the most debilitating diseases, causing profound physical and psychological impacts on patients. The global number of cancer patients has been steadily rising over the last few decades. The development of effective cancer therapies remains the primary focus in life science research, requiring a precise understanding of ...
Anupom Deb Nath, Yousuf Alam, Afsana Mustak Mim, Maksuda Akter, Mohammad Abbas Gani, Khondaker Muhammad Khairul Alam, Md. Nur Alam   +6 more
wiley   +1 more source

When Meningioma Travels: Rare Extracranial Metastasis—Case and Review

Clinical Case Reports, Volume 14, Issue 4, April 2026.
Recurrent atypical meningioma with anaplastic transformation (Grade 3) developed delayed hepatic metastasis 12 years after diagnosis. Biopsy confirmed metastatic meningioma. Treatment with Sandostatin and Everolimus stabilized disease before progression, highlighting the need for long‐term surveillance in high‐risk cases.
Tala Najdi, Sami Abi Farraj, Pierre El Sett, Clarisse Kattan, Antoine El Sett, Antoine Chartouni, Patrick Ghorayeb, Ghadi Dagher, Rhea Khazen, Fares Azoury, Joseph Kattan, Hampig Kourie   +11 more
wiley   +1 more source

Strategies for Innovative Development of Tumor-targeted Theranostic Radiopharmaceuticals

Yuanzineng kexue jishu
Radiopharmaceutical is an essential component of nuclear medicine and have demonstrated significant potential in disease diagnosis and treatment. In recent years, several tumor-targeted theranostic radiopharmaceuticals have been approved for market ...
HUANG Xuhu1, 2, 3, CHEN Huan1, 2, 3, LI Kexin1, 2, 3, WANG Ning1, 2, 3, ZHUANG Jin1, 2, 3, LI Hongyu1, 2, 3, DU Jin2, 3, 4
doaj   +1 more source

Ultrasmall Au10–12 Nanoclusters: A Novel Platform for 223Ra‐Targeted Tumor α‐Therapy

Exploration, Volume 6, Issue 2, April 2026.
Encapsulating 223Ra in Au10‐12 nanoclusters and functionalizing them with RGD peptides enables targeted α‐therapy and immune microenvironment remodeling in non‐osseous tumors like triple‐negative breast cancer. This study establishes a foundational framework for novel 223Ra‐labeled α‐radiopharmaceuticals and shows strong potential for clinical ...
Yifei Jiang, Huizhen Yang, Guoping Jia, Wangxi Hai, Rongyi Huang, Peng Wang, Min Zhang, Danni Li, Yizhou Chen, Xiao Li, Biao Li, Chunfu Zhang   +11 more
wiley   +1 more source

Radionuclide theranostics: advances and clinical applications in lung cancer

Frontiers in Oncology
Lung cancer remains a leading cause of global cancer deaths, underscoring the urgent need for more accurate diagnostic and treatment approaches. Radionuclide theranostics has rapidly emerged as a paradigm that couples molecular imaging with targeted ...
Yang Yang, Yang Yang, Jiang Fu, ShengJie Tang, Tao Liu, HaiYang Hu, HaiYang Guo, Long Wen, Long Wen, YunLong Yang, YunLong Yang, ChengKuan Liu, ChengKuan Liu, YiXin Zhang, Li Yu, HaiNing Zhou, HaiNing Zhou, HaiNing Zhou, HaiNing Zhou   +18 more
doaj   +1 more source