Results 71 to 80 of about 13,805 (198)

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source

Combination Strategies and Targeted Radionuclide Therapies

Seminars in Nuclear Medicine
Combination models utilising treatments from two or more therapeutic classes are well established in cancer care. In the new era of theranostic (theragnostic) medicine there is an ongoing need to identify and refine novel combination strategies to optimise multidisciplinary care for conditions commonly encountered in nuclear medicine such as ...
Kerry Jewell, Louise Kostos, Brittany Emmerson, Michael S. Hofman   +3 more
openaire   +3 more sources

Controlled Synthesis of a New Class of Heterostructured Metal Oxides (Cerium, Thorium, Uranium)/Calcium Fluoride Core‐Shell Nanocrystals With Atomically Coherent Interfaces

Angewandte Chemie, Volume 138, Issue 12, 16 March 2026.
Precisely engineered heterostructured metal oxide‐based MO2 / CaF2 (M = Ce, Th, U) core‐shell nanocrystals are synthesized with atomic‐level control over size, shell thickness, and interface coherence, expanding heterostructure design principles to cerium oxide and actinide oxide systems for the first time.
Dejing Meng, Radian Popescu, Carmen M. Andrei, Jérôme Himbert, Eduard Madirov, Jacob A. Branson, Emily M. Reynolds, Tim Prüßmann, Jörg Göttlicher, Tonya Vitova, Niko Hildebrandt, Yolita Eggeler, Bryce S. Richards, Olaf Walter, Damien Hudry   +14 more
wiley   +2 more sources

Occupational burnout in nuclear medicine technologists working in Australia and New Zealand – results of a multi‐national survey

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 25-33, March 2025.
Occupational burnout is associated with negative feelings about the workplace and is often caused by a high workload and a non‐supportive workplace. It is associated with absenteeism, high turnover of staff and decreased patient care. More than half of the New Zealand participants and three quarters of the Australian participants had moderate levels of
Melissa Shields, Daphne James, Lynne McCormack   +2 more
wiley   +1 more source

Targeted Radionuclide Therapy

, 2022
The aim of this work is to improve the current computational dosimetry approaches for in vitro and in vivo TRT treatment in order to correlate microdosimetry with biological effects. The creation of such computational frameworks and the investigation of the radiobiology of dose-response in TRT in cells and in small animals can ultimately lead to a ...
openaire   +1 more source

Molecular theranostics: principles, challenges and controversies

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 156-164, March 2025.
Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley   +1 more source

Lead-212 Radiopharmaceuticals for Receptor-Targeted Radionuclide Therapy [PDF]

Journal of Mazandaran University of Medical Sciences
Receptor-targeted radionuclide therapy (RTRT) combines the power of particle-emitting radionuclides with the receptor-targeting capabilities of biomolecules, including antibodies and peptides.
Solmaz Mojarad-Jabali, Sajjad Molavipordanjani   +1 more
doaj  

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet, Klas Petersson, Marc C. Huisman, C. Willemien Menke‐van der Houven van Oordt, Iris H. C. Miedema, Andrea Thiele, Ghazal Montaseri, Alejandro Pérez‐Pitarch, David Busse   +8 more
wiley   +1 more source

Global Trends Survey for Targeted Radionuclide Therapy

Japanese Journal of Radiological Technology, 2018
Radionuclide therapy has been used to help manage a range of diseases and has a role of growing importance, with an increasing impact on clinical practice globally. A survey in the field of Radionuclide therapy was conducted by reviewing 4199 science abstracts of main conference (Japanese Society of Radiological Technology, Japanese Society of Nuclear ...
Kohei, Hanaoka, Takamasa, Maeda, Noriaki, Miyaji, Kenta, Sakaguchi, Hiroto, Yoneyama, Matsuyoshi, Ogawa, Hiroyuki, Tsushima   +6 more
openaire   +3 more sources

Cutting‐edge advances in bicyclic peptide‐based radiotracers for cancer imaging and theranostics

VIEW, EarlyView.
Abstract Along with successful clinical approval of radiopharmaceuticals targeting somatostatin receptor subtype 2 and prostate‐specific membrane antigen, peptide‐based radiotracers have garnered the increasing attention in cancer imaging and theranostics. As a newly emerging targeting ligand in recent years, bicyclic peptides have demonstrated immense
Hengyi Ou, Xiaobo Wang, Fei Kang
wiley   +1 more source