Results 91 to 100 of about 8,056 (296)

Targeted Sanctions and Deterrence in the Twenty-first Century

, 2020
The use of sanctions is often associated with coercion and deterrence. The former implies that sanctions contribute to changing the behaviour of targets, while the latter suggests that the damage threatened by sanctions should discourage actors from ...

core  

Pipeline politics: Russian energy sanctions and the 2010 Ukrainian elections

Journal of Eurasian Studies, 2013
In early 2010, the ‘Orange Revolution’ in the Ukraine came to an end. The pro-Western President, Viktor Yushchenko, was replaced by the pro-Russian Viktor Yanukovych.
Randall E. Newnham
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

African sanctions The case of Burundi

, 2005
[The book:] The main theme of the book is that the new types of sanctions constitute a challenge to the international system. First, there are more of the targeted sanctions, including financial, travel, aviation, special commodity and arms sanctions ...
Wohlgemuth, Lennart,
core  

Economic sanctions and just war theory: the case for specific targeted sanctions

In this paper we distinguish, from other sanctions, specific targeted sanctions—namely those imposed on particular individuals and sanctions on goods that facilitate the violation of human rights.
Marinovic Guijon, Alejandra Cristina, Arancibia Collao, Fernando Andrés, Guajardo Ortega, Constanza Carolina   +2 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

EU THEMATIC SANCTIONS REGIMES [PDF]

Научно-аналитический вестник Института Европы РАН
An important element of Western actors’ sanctions toolkit is thematic, or horizontal, programs of restrictive measures designed to address transnational problems and exert pressure on violators of international norms. This article examines the specifics,
Lida D. Oganisyan
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Are European Union sanctions “targeted”?

Cambridge Review of International Affairs, 2016
AbstractThe emergence of targeted sanctions in the mid-1990s was due to the humanitarian impact of embargoes, which were deemed unacceptable and compelled senders to shift to measures designed to affect only wrongdoers. Twenty years on, the present paper considers the extent to which autonomous sanctions are designed to affect those individuals and ...
openaire   +3 more sources