Results 151 to 160 of about 159,655 (310)

Prioritizing Health in War and Conflict: The 2025 War in Iran and the Call for Global Peace. [PDF]

Int J Health Policy Manag
Raoofi A, Ehsani-Chimeh E, Takian A.
europepmc   +1 more source

Sanctions on South Africa: What Did They Do [PDF]

This paper considers the economic sanctions that were applied in the mid-1980s to pressure the South African government to end apartheid. It asks what role those sanctions played in the eventual demise of the apartheid regime and concludes that the role ...
Philip I. Levy
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Attitudes and behaviours on driving under the influence of drugs: a multigroup analysis of non-drug users and people who use methamphetamine. [PDF]

Harm Reduct J
Mackay A, Downey LA, Arunogiri S, Ogeil RP, Hayley AC.   +4 more
europepmc   +1 more source

The Impact of Economic Sanctions on US Trade: Andrew Rose's Gravity Model [PDF]

With the end of the Cold War, the focus of US foreign policy changed--and so did that of economic sanctions. Partly because of increased cooperation within the UN framework, economic sanctions were imposed so routinely in the early 1990s that scholars ...
Barbara Oegg, Gary Clyde Hufbauer
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Iran's humanitarian crisis: war, legality, and the erosion of population health. [PDF]

Lancet Reg Health Eur
Blanchet K, Barakat S, Kumar B, Spiegel P.   +3 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

From violation to stigma: a literature review of athletes' lived experiences following anti-doping sanctions. [PDF]

Front Sports Act Living
Lockett I, Blank C, Patterson L, Westmattelmann D, Lux D, Petróczi A.   +5 more
europepmc   +1 more source

Economic Agendas in Civil Wars: What We Know, What We Need to Know [PDF]

civil war, conflict prevention, human ...
Malone, David M., Nitzschke, Heiko
core