Results 131 to 140 of about 1,011,686 (269)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Biological targeted therapy for lupus nephritis-the role of BLYS and APRIL. [PDF]

Ren Fail
Yang X, Liu S, Liu XJ, Wen D, Zhou Y, Zeng Y, Li L, Deng Q, Wang Y, Chen Q, Lv J.   +10 more
europepmc   +1 more source

Siglecs as targets for therapy in immune-cell-mediated disease

, 2009
Mary K. O’Reilly, James C. Paulson
openalex   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Multivalently engineered glyco-nanoplatforms for targeted therapy and diagnostics. [PDF]

Chem Sci
Zhang XL, Ding H, Zheng JY, Cao H, Liu XW.   +4 more
europepmc   +1 more source

Selection of radionuclide(s) for targeted alpha therapy based on their nuclear decay properties

Samantha M. Ree, Howard Greenwood, Jennifer D. Young, Rachel Roberts, Francis R. Livens, S.L. Heath, Jane Sosabowski   +6 more
openalex   +1 more source

The Tipping Point for Combination Therapy: Cancer Vaccines With Radiation, Chemotherapy, or Targeted Small Molecule Inhibitors

, 2012
James W. Hodge, Andressa Ardiani, Benedetto Farsaci, Anna Kwilas, Sofia R. Gameiro   +4 more
openalex   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Targeted therapy of papillary craniopharyngioma. [PDF]

Med Oncol
Luo N, Lin Y, Hong T, Lin Z.
europepmc   +1 more source

Glycan-Targeted Virus-like Nanoparticles for Photodynamic Therapy

, 2012
Jin‐Kyu Rhee, Michael M. Baksh, Corwin M. Nycholat, James C. Paulson, Hiroaki Kitagishi, M. G. Finn   +5 more
openalex   +2 more sources