Results 171 to 180 of about 24,679,585 (287)

Whole‐Brain Diffusion MRI at 7T With Universal Multiband GRAPE pTx Pulses

Magnetic Resonance in Medicine, EarlyView.
Purpose To improve signal strength and homogeneity of whole‐brain diffusion‐weighted imaging (DWI) at 7T. Methods Universal multiband excitation and refocusing pulses were optimized with the gradient ascent pulse engineering (GRAPE) algorithm across a database of B1+$$ {B}_1^{+} $$ and B0$$ {B}_0 $$ maps obtained from 20 subjects.
Marten Laufenberg, Daniel Löwen, Mónica Ferreira, Nicolas Boulant, Jennifer Faber, Tony Stöcker   +5 more
wiley   +1 more source

Accelerated Motion‐Compensated Diffusion‐Weighted pCASL Using Subspace Low‐Rank Reconstruction for Quantification of BBB Water Exchange and Permeability

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop an accelerated motion‐compensated diffusion‐weighted pseudo‐continuous arterial spin labeling (MCDW‐pCASL) method using a spatial subspace low‐rank reconstruction method for efficient quantification of blood–brain barrier (BBB) water exchange (kw) and permeability (PSw).
Zixuan Liu, Chenyang Zhao, Ziyang Huang, Fanhua Guo, Danny J. J. Wang, Xingfeng Shao   +5 more
wiley   +1 more source

Brain reward function in young people with cannabis use disorder: A functional magnetic resonance imaging study

Addiction, EarlyView.
Abstract Background and Aims Cannabis use disorder (CUD) affects ~50 million people globally. Neuroscientific theories suggest that a blunted neural response to non‐drug rewards is a hallmark of substance use disorders; however, this remains untested in CUD. The current study tested whether brain reward system responses to the anticipation and feedback
Martine Skumlien, Lisa‐Marie Greenwood, Arush Honnedevasthana Arun, Isabella Goodwin, Anastasia Paloubis, Tribikram Thapa Rana, Marianna Quinones Valera, Eugene McTavish, Gabrielle Abbott, Suraya Dunsford, Antonio Verdejo‐Garcia, Jessica Ramamurthy, Mark M. Schira, Nadia Solowij, Chao Suo, Valentina Lorenzetti   +15 more
wiley   +1 more source

Effects of Noninvasive Cervical Vagal Nerve Stimulation on Cognitive Performance But Not Brain Activation in Healthy Adults

Neuromodulation: Technology at the Neural Interface, EarlyView., 2020
Abstract Objectives While preliminary evidence suggests that noninvasive vagal nerve stimulation (nVNS) may enhance cognition, to our knowledge, no study has directly assessed the effects of nVNS on brain function and cognitive performance in healthy individuals.
Ruth Klaming, Alan N. Simmons, Andrea D. Spadoni, Imanuel Lerman   +3 more
wiley   +1 more source

Phase coupling between eye and brain pulsations is bidirectional and modulated by the parasympathetic system – An fMREye study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Physiological pulsations driven by cardiac, respiratory, and vasomotor activity are essential for solute transport within perivascular and perineural cerebrospinal fluid (CSF) pathways that support brain and eye clearance systems. Previous studies have shown that parasympathetic blockade significantly reduces ocular pulsation power and
Ebrahimi Seyed‐Mohsen, Väyrynen Tommi, Huotari Niko, Saarela Ville, Honkamo Marja, Helakari Heta, Järvelä Matti, Korhonen Vesa, Raitamaa Lauri, Kiviniemi Vesa   +9 more
wiley   +1 more source

Safety pharmacology of acute mescaline administration in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber, Mélusine Humbert‐Droz, Laura Ley, Yasmin Schmid, Matthias E. Liechti   +4 more
wiley   +1 more source

Associations between maths ability mindset, maths task preference and physiological responses to feedback during an arithmetic task across two primary school years

British Journal of Educational Psychology, EarlyView.
Abstract Background Students' mindsets, reactions to feedback and learning‐related behaviour are important for academic success, yet little is known about how these factors and their interconnections develop during primary school. Aims To explore longitudinal associations between students' mindsets, physiological responses to performance feedback, and ...
Ita Puusepp, Tuisku Tammi, Tanja Linnavalli, Minna Huotilainen, Sonja Laine, Kirsi Tirri   +5 more
wiley   +1 more source

Sustained attention in dementia with Lewy bodies: a task-based fMRI study. [PDF]

Front Aging Neurosci
Braghittoni D, Venturi G, Guidi L, Capogna E, Sighinolfi G, Baldelli L, Amore G, La Morgia C, Sambati L, Venneri A, Lodi R, Tonon C, Mitolo M.   +12 more
europepmc   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) C.M. de Lange   +26 more
wiley   +1 more source

Disentangling the effect of brain insulin resistance on brain health (BIR‐BrainHealth): Rationale and study protocol

Diabetic Medicine, EarlyView.
Abstract Aims Insulin signalling in the brain is crucial for systemic metabolic regulation and cognitive function. In some individuals, these effects are reduced, a phenomenon referred to as brain insulin resistance (BIR). This condition may contribute to the elevated risk of cognitive decline and dementia in diabetes, yet its prevalence, mechanisms ...
Sabrina Wangler, Peter Sørensen, Konni Kass, Nicole Jaqueline Jensen, Mark Bitsch Vestergaard, Julia Hummel, Ronja Völk, Julie Christine Antvorskov, Flemming Pociot, Jørgen Rungby, Martin Heni, Henrik Bo Wiberg Larsson   +11 more
wiley   +1 more source