Results 81 to 90 of about 2,919,908 (303)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Fog Offloading and Task Management in IoT-Fog-Cloud Environment: Review of Algorithms, Networks, and SDN Application

open access: yesIEEE Access
The proliferation of Internet of Things (IoT) devices and other IT forms in almost every area of human existence has resulted in an enormous influx of data that must be managed and stored.
Mohammad Reza Rezaee   +3 more
doaj   +1 more source

A queueing model of pilot decision making in a multi-task flight management situation [PDF]

open access: yes, 1978
Allocation of decision making responsibility between pilot and computer is considered and a flight management task, designed for the study of pilot-computer interaction, is discussed.
Rouse, W. B., Walden, R. S.
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Development of an OpenAI-Based Solution for Decision-Making

open access: yesApplied Sciences
This study explores the development of an Open Artificial Intelligence (AI) decision-making solution, integrating blockchain technology with artificial intelligence to streamline organizational decision-making processes.
Sergiu Manolache, Nirvana Popescu
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organisations and workloads: a ‘health check’: annex a of building a safe, confident future: the final report of the Social Work Task Force [PDF]

open access: yes, 2009
This document is Annex A of 'Building a safe, confident future - The final report of the Social Work Task Force' which was published in November 2009. This Annex is provided to support organisations to undertake a self assessment against the 5 key areas,

core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Task Force : Task Management System

open access: yes
This preprint presents a Task Management System. This study introduces a task management system that helps the user by taking the load of organizing tasks according to their priority. The system first authenticates the user using email and password. A user can provide a task name, a task description and a due date and also set a priority (low, medium ...
Nikita Yadav, Pari Agarwal
openaire   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

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