Results 121 to 130 of about 2,689,429 (376)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

International cooperation for developmen: Design of a competence-based model for managing programmes and projects [PDF]

open access: yes, 2010
Managing international cooperation for development projects is a complex task that involves technical, political, socio-economic and cultural variables.
Cobo Benita, José Ramón   +2 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Flat-plate solar array project. Volume 8: Project analysis and integration [PDF]

open access: yes
Project Analysis and Integration (PA&I) performed planning and integration activities to support management of the various Flat-Plate Solar Array (FSA) Project R&D activities. Technical and economic goals were established by PA&I for each R&D task within
Henry, P., Mcguire, P.
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Why It Worked: Critical Success Factors of a Financial Reform Project in Africa [PDF]

open access: yes
Little is written about the critical success factors that make or break a project implementing a public financial management reform in Africa. Based on the twelve year experience of Harvard's DSA project which transformed Ethiopia's financial management ...
Peterson, Stephen
core   +1 more source

Project uncertainty, project risk and project leadership : a policy capturing study of New Zealand project managers : a thesis presented in partial fulfillment of the requirements for the degree of Master of Arts in Psychology at Massey University, Wellington, New Zealand [PDF]

open access: yes, 2016
Cooperation between project practice and project research could help reduce failure rates for projects in New Zealand and globally. The current research used a “policy capturing” method - systematically varying sources of project uncertainty (policy ...
Mercer, Brendon
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Models and methods of the technological maturity development of self-managed organizations in the context of using the syncretic methodology [PDF]

open access: yesДороги і мости
Introduction. Infrastructure restoration projects of Ukraine are being implemented in the difficult conditions of war and many challenges. To increase the effectiveness of their implementation, project-oriented organizations need an effective management ...
Andrii Ivko
doaj   +1 more source

Design project planning, monitoring and re-planning through process simulation [PDF]

open access: yes, 2009
Effective management of design schedules is a major concern in industry, since timely project delivery can have a significant influence on a company’s profitability.
Clarkson, PJ, Wynn, DC
core  

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