Results 81 to 90 of about 3,354,478 (288)

Peer counseling for perinatal depression in low- and middle-income countries: A scoping review

Cambridge Prisms: Global Mental Health
Perinatal depression is associated with adverse maternal, newborn and child health outcomes. Treatment gaps and sociocultural factors contribute to its disproportionate burden in low- and middle-income countries (LMICs).
Alexander Cuncannon, Kailyn Seitz, Aneel Singh Brar, Aliyah Dosani   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Development of a scoring system for non-specialist ratings of clinical competence in global mental health: a qualitative process evaluation of the Enhancing Assessment of Common Therapeutic Factors (ENACT) scale

Cambridge Prisms: Global Mental Health, 2015
Background. Task-sharing is the involvement of non-specialist providers to deliver mental health services. A challenge for task-sharing programs is to achieve and maintain clinical competence of non-specialists,
B. A. Kohrt, M. K. Ramaiya, S. Rai, A. Bhardwaj, M. J. D Jordans   +4 more
doaj   +1 more source

Merit overrules theory of mind when young children share resources with others.

PLoS ONE, 2020
Non-windfall approaches to sharing demonstrate pre-schoolers' sensitivity to merit-based distributions of resources. However, such studies have not considered (1) whether epistemic aspects of task performance, such as the relative accuracy of a co-worker,
James Stack, Carlos Romero-Rivas
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Efficient Multi-Task Reinforcement Learning via Selective Behavior Sharing

, 2023
The ability to leverage shared behaviors between tasks is critical for sample-efficient multi-task reinforcement learning (MTRL). While prior methods have primarily explored parameter and data sharing, direct behavior-sharing has been limited to task ...
Lim, Joseph J., Zhang, Grace, Sun, Shao-Hua, Jain, Ayush, Hwang, Injune   +4 more
core  

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Illinois Terrorism Task Force- 2008 Annual Report [PDF]

, 2009
This report documents the activities and accomplishments of the Illinois Terrorism Task Force during the year 2008.not peer reviewedSubmitted by Adam Groves (agroves@illinois.edu) on 2010-03-08T17:27:06Z No. of bitstreams: 1 Illinois Terrorism Task Force-
Illinois Terrorism Task Force
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