Results 191 to 200 of about 4,955 (252)

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

Exploring the current usage of and attitudes towards transanastomotic tube (TAT) feeding in infants born with duodenal atresia: a survey of practice in the UK. [PDF]

BMJ Paediatr Open
Jager A, Turnbull J, Johnson MJ, Hall NJ.   +3 more
europepmc   +1 more source

(Fe4N/GaN)@GC: A Bifunctional Electrocatalyst for High‐Performance Rechargeable Zinc‐Air Batteries

Advanced Science, EarlyView.
This work demonstrates that an unprecedented Fe4N/GaN heterostructure, stabilized by a graphitized carbon shell, induces interfacial charge redistribution and optimizes oxygen‐intermediate adsorption, enabling highly efficient bifunctional ORR/OER electrocatalysis for rechargeable zinc‐air batteries.
Xin‐Yuan Wei, Sai‐Sai Xie, Xia‐Li Ding, Yuan‐Qi Zhai, Sen Yu, Xiang‐Quan Hu, Rongqian Wu, Jintao Lu, Yan‐Zhen Zheng   +8 more
wiley   +1 more source

The frequencies of nucleotides, codons and amino acids in highly expressed genes [PDF]

, 2006
Tats, Age
core  

Single-molecule methods for characterizing receptor dimers reveal metastable opioid receptor homodimers that induce functional modulation. [PDF]

Nat Commun
Zhou P, Tsunoyama TA, Kasai RS, Hirosawa KM, Kalay Z, Aladag A, Fujiwara TK, Yokoyama T, Sakamoto M, Kise R, Yanagawa M, Inoue A, Pigolotti S, Kusumi A.   +13 more
europepmc   +1 more source

Wearable Electro‐Thermal Haptic Stimulator Driven by a Self‐Powered Tactile Sensor for Realistic Stimulus Replication

Advanced Science, EarlyView.
We present a stimulus‐replicating system combining a tactile sensor with a wearable Peltier thermotactile module and concentric electrotactile electrode. Signals encoding pressure and temperature drive the stimulators to reproduce mechano‐thermal cues on the skin. AlN/PDMS encapsulation and SA/LA PSA ensure mechanical compliance and thermal efficiency.
Ey‐In Lee, Chae‐Young Kang, Kyuhyun Hwang, Jongbaeg Kim, Jin‐Woo Park   +4 more
wiley   +1 more source

Turnaround Time and Patients' Perceptions of Clinical Laboratory Services at a Tertiary Hospital in Pakistan: A Cross-Sectional Study. [PDF]

Health Sci Rep
Basit AA, Usman M, Fakih N, Akram L, Nighat A, Rehman ZU.   +5 more
europepmc   +1 more source

A Global Methane Observation System to Reduce Uncertainty for Anthropogenic and Natural Sources and Sinks for Detecting and Attributing Climate Feedbacks

Advanced Science, EarlyView.
Conceptual illustration of a Global Ecosystem Methane Observing System (GEM‐OS) integrating satellites, aircraft, atmospheric networks, and ecosystem measurements to quantify methane emissions from anthropogenic and natural sources. The multi‐scale observing framework improves source attribution, reduces uncertainty in regional methane budgets, and ...
P. Ciais, S. Peng, J. Chang, F. Li, Q. Zhu, K. Yuan, G. Hugelius, H. Li, Y. Cai, F. Chevallier, K. Tibrewal, E. A. Kort, K. Arndt, J. Watts, B. Buma, N. Besic, P. I. Palmer, H. Cadillo‐Quiroz, E. Euskirchen, M. J. Gondwe, A. Hoyt, R. Jackson, S. Malone, D. Monteverde, S. Natali, M. Ramonet, C. Rey‐Sanchez, L. B. Sagang, E. A. G. Schuur, R. Vargas, R. Varner, Z. Zhang, B. Poulter   +32 more
wiley   +1 more source

Excitation and mechanical contraction of a 3D cardiomyocyte model. [PDF]

Biophys J
Hatano A, Mochizuki Y, Sakakima H, Izumi S, Hoshijima M, Ellisman M, McCulloch AD.   +6 more
europepmc   +1 more source

A Dual‐Modal Wearable PPG Smartwatch with AI‐Enhanced Correction for High‐Accuracy and Continuous AF Burden Assessment

Advanced Science, EarlyView.
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo, Jinglei Wang, Xin Wang, Han Feng, Yize Zhao, Fadong Li, Shaobin Wei, Le Zhou, Zixu Zhao, Songjie Chen, Xiangyi Kong, Jue Wang, Liu He, Shijun Xia, Xin Li, Junmeng Zhang, Xiaoxia Liu, Xueyuan Guo, Ning Zhou, Songnan Li, Chenxi Jiang, Ribo Tang, Caihua Sang, Deyong Long, Xin Du, Jianzeng Dong, Wenwu Zhu, Changsheng Ma   +27 more
wiley   +1 more source