Results 91 to 100 of about 925,069 (322)

Chemical Synthesis of Microtubule-Associated Protein Tau 2N4R [PDF]

, 2023
Wyatt C. Powell, Ruiheng Jing, Maciej A. Walczak   +2 more
openalex   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Spin Fluctuation-Induced Superconductivity in Organic Compounds

, 1998
Spin fluctuation-induced superconductivity in two-dimensional organic compounds such as \kappa-(ET)_2-X is investigated by using a simplified dimer Hubbard model with right-angled isosceles triangular lattice (transfer matrices -\tau, -\tau^\prime).
Anderson P. W., Bickers N. E., Dahm T., Kanoda K., Kawamoto A., Kino H., Koikegami S., Kontani H., Langer M., Mayaffre H., Miyake K., Monthoux P., Monthoux P., Moriya T., Nakamura S., Oshima K., Pao C.-H., Saito G., Schirber J. E., Sushko Yu. V., Takimoto T.   +20 more
core   +1 more source

An Exploratory Study on the Effect of Petroleum Hydrocarbon on Soils Using Hyperspectral Longwave Infrared Imagery

Remote Sensing, 2019
Manmade crude oil contamination, which has negative impacts on the environment and human health, can be found in various ecosystems all over the globe.
Ran Pelta, Eyal Ben-Dor
doaj   +1 more source

Polyserine-tau interactions modulate tau fibrillization

Journal of Biological Chemistry
AbstractTau aggregates are the defining feature of multiple neurodegenerative diseases and contribute to the pathology of disease. However, the molecules affecting tau aggregation in cells are unclear. We previously determined that polyserine-rich domain containing proteins enrich in tau aggregates, assemble into puncta that can serve as sites of tau ...
James Pratt, Kathleen McCann, Jeff Kuo, Roy Parker   +3 more
openaire   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

P and T Odd Asymmetries in Lepton Flavor Violating Tau Decays

, 2000
We calculated the differential cross sections of the processes in which one of the pair created tau particles at an e^+ e^- collider decays into lepton flavor violating final states e.g. tau -> mu gamma, tau -> 3 mu, tau -> mu ee.
A. Aeppli, A. E. Faraggi, A. H. Chamseddine, A. Pais, B. Ananthanarayan, B. Ananthanarayan, B. K. Bullock, B. K. Bullock, C. A. Nelson, C. A. Nelson, C. A. Nelson, C. A. Nelson, C. Bouchiat, D. Atwood, F. Borzumati, G. Couture, G. Couture, H. Kühn, J. Bernabeu, J. Bernabeu, J. Bernabéu, J. Ellis, J. Hisano, J. Hisano, J. Hisano, J. Hisano, J. Hisano, J. Sato, K. Fujikawa, L. Hall, L. J. Hall, L. Michel, M. Gell-Mann, N. Arkani-Hamed, P. Privitera, R. Alemany, R. Barbieri, R. Barbieri, R. Barbieri, R. Kitano, R. Kitano, Ryuichiro Kitano, S. Ahmed, S. Goozovat, S. Kawasaki, S. Pi, S. Pi, T. Hagiwara, T. P. Cheng, T. Yanagida, W. Bernreuther, W. Bernreuther, W. Buchmüller, W. Buchmüller, W. Fetscher, Y. Fukuda, Y. Grossman, Y. Kuno, Y. Kuno, Y. Okada, Y. Okada, Y. S. Tsai, Y. Tsai, Yasuhiro Okada   +63 more
core   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Forecast changes in the productivity of plant communities in the Pre-Urals Steppe site of Orenburg State Nature Reserve (Russia) in extreme drought conditions using NDVI

Nature Conservation Research: Заповедная наука, 2019
The normalised-difference vegetative index (NDVI) seasonal dynamics of 15 types of vegetation communities in dry 2010 and in 2016 with a favourable weather conditions was studied in the Pre-Urals Steppe site where the Programme on establishing a semi ...
Nikolay I. Fedorov, Tatjana L. Zharkikh, Oksana I. Mikhailenko, Rafilia T. Bakirova, Vasiliy B. Martynenko   +4 more
doaj   +1 more source