Results 11 to 20 of about 212,588 (266)
Tau is a microtubule-associated protein that plays an important role in axonal stabilization, neuronal development, and neuronal polarity. In this review, we focus on the primary, secondary, tertiary, and quaternary tau structures. We describe the structure of tau from its specific residues until its conformation in dimers, oligomers, and larger ...
Jesus Avila +9 more
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In this short review, I will focus on how a unique tau gene may produce many tau isoforms through alternative splicing and how the phosphorylation of these isoforms by different kinases may affect their activity and behaviour. Indeed, each of the different tau isoforms may play a distinct role under both physiological and pathological conditions. Thus,
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Tau Pathology Generated by Overexpression of Tau [PDF]
Neurofibrillary changes of abnormally hyperphosphorylated tau are the key lesion in Alzheimer’s disease (AD) and a number of other tauopathies. Recent developments in the field of autosomal dominantly inherited dementias, in particular the frontotemporal dementias and Parkinsonism linked to chromosome 17 (FTDP-17) group, have shown that abnormalities ...
I, Grundke-Iqbal, K, Iqbal
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Tau here, tau there, tau almost everywhere: Clarifying the distribution of tau in the adult CNS
AbstractThe microtubule‐associated protein tau has gained significant attention over the last several decades primarily due to its apparent role in the pathogenesis of several diseases, most notably Alzheimer's disease. While the field has focused largely on tau's potential contributions to disease mechanisms, comparably less work has focused on normal
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Here we revisit tau protein aggregation at primary, secondary, tertiary and quaternary structures. In addition, the presence of non-aggregated tau protein, which has been recently discovered, is also commented on.
Hernández, Félix +5 more
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16 pages, 8 figures. Invited talk at the XIX International Symposium on Lepton and Photon Interactions at High Energies (Stanford, August 1999)
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Accumulated Mixed Precipitation Estimation Using Measurements from Multiple Microwave Links
Recently, microwave communication networks have been shown to be valuable tools for rainfall monitoring, based on the well-known Power-Law which relates rain-rate to attenuation in microwave frequencies.
Jonatan Ostrometzky +2 more
doaj +1 more source
In 2015, the Joint Directorate of State Nature Reserves «Orenburg» and «Shaitan-Tau» (FSFI «Orenburg Reserves») launched the Programme on establishing a semi-free population of the Przewalski's horse Equus ferus przewalskii in the 165 km2 Pre-Urals ...
Daniel Klich +5 more
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Precision agriculture is crucial for ensuring food security in a growing global population. Nutrients, their presence, concentration, and effectiveness, are key components in data-driven agriculture.
Harpreet Singh +5 more
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The first successful reintroduction programme for the Przewalski's horse in Russia was launched by FSFI «Orenburg Reserves» in 2015. A total of 36 Przewalski's horses were brought to the Pre-Urals Steppe site from semi-reserves in France and Hungary in ...
Tatjana L. Zharkikh +7 more
doaj +1 more source

