Results 221 to 230 of about 212,588 (266)

Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments. [PDF]

Elife
Lövestam S, Wagstaff JL, Katsinelos T, Shi J, Freund SMV, Goedert M, Scheres SHW.   +6 more
europepmc   +1 more source

Influence of an AQP4 haplotype and sleep duration on early Alzheimer's disease. [PDF]

Alzheimers Dement
Palatsides EL, Yiallourou S, Himali D, Cavuoto MG, Baril AA, Yang Q, Peloso GM, Ryan J, El Fakhri G, Ghosh S, Thibault E, DeCarli CS, Johnson KA, Beiser AS, Seshadri S, Himali JJ, Pase MP.   +16 more
europepmc   +1 more source

La noción de la muerte como objeto de investigación de la psicología del desarrollo

Cuadernos de Neuropsicología, 2014
Ramiro Tau
doaj  

Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases [PDF]

Journal of Neurochemistry, 2009
AbstractTau is a neuronal microtubule‐associated protein. Its hyperphosphorylation plays a critical role in Alzheimer disease (AD). Expression and phosphorylation of tau are regulated developmentally, but its dynamic regulation and the responsible kinases or phosphatases remain elusive.
Cheng-Xin Gong, Fei Liu, Khalid Iqbal
exaly   +3 more sources

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Tau Aggregates and Tau Pathology

Journal of Alzheimer's Disease, 2008
There is controversy in some neurodegenerative disorders whether the presence of aberrant aggregates in a neuron could have a toxic or a protective effect. In some disorders like in encephalopathies (prion disease), protein aggregates are toxic for the neuron.
Hernández, Félix, Ávila, Jesús
openaire   +3 more sources

Plasma tau complements CSF tau and P‐tau in the diagnosis of Alzheimer's disease

Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 2019
AbstractIntroductionPlasma tau may be an accessible biomarker for Alzheimer's disease (AD), but the correlation between plasma and cerebrospinal fluid (CSF) tau and the value of combining plasma tau with CSF tau and phospho‐tau (P‐tau) are still unclear.MethodsPlasma‐tau, CSF‐tau, and P‐tau were measured in 97 subjects, including elderly cognitively ...
Jingyun Chen, Jamie Toombs, KAJ Blennow   +2 more
exaly   +5 more sources

Tau protein and tau aggregation inhibitors

Neuropharmacology, 2010
Alzheimer disease is characterized by pathological aggregation of two proteins, tau and Abeta-amyloid, both of which are considered to be toxic to neurons. In this review we summarize recent advances on small molecule inhibitors of protein aggregation with emphasis on tau, with activities mediated by the direct interference of self-assembly.
Bulic, B., Pickhardt, M., Mandelkow, E., Mandelkow, E.   +3 more
openaire   +3 more sources

Tau and Tauopathies

Neurology India, 2007
Tau protein is a neuronal microtubule-associated protein (MAP), which localizes primarily in the axon. It is one of the major and most widely distributed MAPs in the central nervous system. Its biochemistry and molecular pathology is being increasingly studied. Tau is a key component of neurofbrillary tangles in Alzheimer's disease (AD). Disorders with
Mathuranath, PS, Robert, M
openaire   +2 more sources

Correlation measurements in Z-]tau(+)tau(-) and the tau-neutrino helicity

1994
Using data collected with the ALEPH detector at LEP correlations between the decay products of the tau(+) and tau- produced in the decay of the Z have been measured. The measurements performed in the decays tau --> pi nu and tau --> p nu place limits on deviations from the Standard Model.
D. Buskulic, I. De Bonis, D. Decamp, P. Ghez, C. Goy, J. P. Lees, M. N. Minard, B. Pietrzyk, F. Ariztizabal, P. Comas, J. M. Crespo, M. Delfino, I. Efthymiopoulos, E. Fernandez, M. Fernandez Bosman, V. Gaitan, L.l. Garrido, T. Mattison, A. Pacheco, C. Padilla, A. Pascual, D. Creanza, M. de Palma, A. Farilla, G. Iaselli, G. Maggi, N. Marinelli, S. Natali, S. Nuzzo, A. Ranieri, G. Raso, F. Romano, F. Ruggieri, G. Selvaggi, L. Silvestris, P. Tempesta, G. Zito, Y. Chai, H. Hu, D. Huang, X. Huang, J. Lin, T. Wang, Y. Xie, D. Xu, R. Xu, J. Zhang, L. Zhang, W. Zhao, G. Bonvicini, J. Boudreau, D. Casper, H. Drevermann, R. W. Forty, G. Ganis, C. Gay, M. Girone, R. Hagelberg, J. Harvey, J. Hilgart, R. Jacobsen, B. Jost, J. Knobloch, I. Lehraus, M. Maggi, C. Markou, M. Martinez, P. Mato, H. Meinhard, A. Minten, R. Miquel, H. G. Moser, P. Palazzi, J. R. Pater, J. A. Perlas, P. Perrodo, J. F. Pusztaszeri, F. Ranjard, L. Rolandi, J. Rothberg, T. Ruan, M. Saich, D. Schlatter, M. Schmelling, F. Sefkow, W. Tejessy, I. R. Tomalin, R. Veenhof, H. Wachsmuth, S. Wasserbaech, W. Wiedenmann, T. Wildish, W. Witzeling, J. Wotschack, Z. Ajaltouni, M. Bardadin Otwinowska, A. Barres, C. Boyer, A. Falvard, P. Gay, C. Guicheney, P. Henrard, J. Jousset, B. Michel, J. C. Montret, D. Pallin, P. Perret, F. Podlyski, J. Proriol, F. Saadi, T. Fearnley, J. B. Hansen, J. D. Hansen, J. R. Hansen, P. H. Hansen, R. Møllerud, B. S. Nilsson, A. Kyriakis, E. Simopoulou, I. Siotis, A. Vayaki, K. Zachariadou, J. Badier, A. Blondel, G. Bonneaud, J. C. Brient, P. Bourdon, G. Fouque, S. Orteu, A. Rougé, M. Rumpf, R. Tanaka, M. Verderi, H. Videau, D. J. Candlin, M. I. Parsons, E. Veitch, E. Focardi, L. Moneta, G. Parrini, M. Corden, C. Georgiopoulos, D. E. Jaffe, D. Levinthal, A. Antonelli, R. Baldini, G. Bencivenni, G. Bologna, F. Bossi, P. Campana, G. Capon, F. Cerutti, V. Chiarella, G. Felici, P. Laurelli, G. Mannocchi, F. Murtas, G. P. Murtas, L. Passalacqua, M. Pepe Altarelli, P. Colrain, I. ten Have, J. G. Lynch, W. Maitland, W. T. Morton, C. Raine, P. Reeves, J. M. Scarr, K. Smith, M. G. Smith, A. S. Thompson, R. M. Turnbull, B. Brandl, O. Braun, C. Geweniger, P. Hanke, V. Hepp, E. E. Kluge, Y. Maumary, A. Putzer, B. Rensch, A. Stahl, K. Tittel, M. Wunsch, R. Beuselinck, D. M. Binnie, W. Cameron, M. Cattaneo, D. J. Colling, P. J. Dornan, J. F. Hassard, N. M. Lieske, A. Moutoussi, J. Nash, S. Patton, D. G. Payne, M. J. Phillips, G. San Martin, J. K. Sedgbeer, A. G. Wright, G. Batignani, CIOCCI, MARIA AGNESE, FERRANTE, ISIDORO, FIDECARO, FRANCESCO, F. Forti, MESSINEO, ALBERTO MARIA, G. Rizzo, TONELLI, GUIDO EMILIO, G. Triggiani, F. Ragusa   +209 more
openaire   +3 more sources