Results 111 to 120 of about 243,600 (356)
RNA stores tau reversibly in complex coacervates.
PLoS Biology, 2017 Nonmembrane-bound organelles that behave like liquid droplets are widespread among eukaryotic cells. Their dysregulation appears to be a critical step in several neurodegenerative conditions.
Xuemei Zhang +8 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2017 The microtubule (MT)-associated protein Tau is a natively unfolded protein, involved in a number of neurodegenerative disorders, collectively called tauopathies, aggregating in neurofibrillary tangles (NFT). It is an open question how the conversion from
Cristina Di Primio +6 more
doaj +1 more source
Corrigendum: Synthetic torpor triggers a regulated mechanism in the rat brain, favoring the reversibility of Tau protein hyperphosphorylation [PDF]
, 2023 Fabio Squarcio +10 more
openalex +1 more source
Advanced Functional Materials, EarlyView.A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang +9 more
wiley +1 more source
HeliyonGeneral anesthesia is significantly gaining prominence and becoming unavoidable in modern medicine. Since neuroprotein fluctuations are common during anesthetic procedures, it is essential to monitor protein levels to identify neuro-related issues.
Hongjuan Gao +4 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Dry electrode technology revolutionizes battery manufacturing by eliminating toxic solvents and energy‐intensive drying. This work details two promising techniques: dry spray deposition and polymer fibrillation. How their unique solvent‐free bonding mechanisms create uniform microstructures for thicker, denser electrodes, boosting energy density and ...
Yuhao Liang +7 more
wiley +1 more source
مجله دانشکده پزشکی اصفهان, 2012 Background: In this study, we evaluated the effects of 6 weeks of voluntary exercise on a running wheel and allium paradoxum on tau protein in the cerebellum of diabetic rats.
Zia Fallah Mohammadi +2 more
doaj
Targeting tau in Alzheimer’s disease: from mechanisms to clinical therapy
Neural Regeneration ResearchAlzheimer’s disease is the most prevalent neurodegenerative disease affecting older adults. Primary features of Alzheimer’s disease include extracellular aggregation of amyloid-β plaques and the accumulation of neurofibrillary tangles, formed by tau ...
Jinwang Ye +3 more
doaj +1 more source
Wild-Type, but Not Mutant N296H, Human Tau Restores Aβ-Mediated Inhibition of LTP in Tau−/− mice
Frontiers in Neuroscience, 2017 Microtubule associated protein tau (MAPT) is involved in the pathogenesis of Alzheimer's disease and many forms of frontotemporal dementia (FTD). We recently reported that Aβ-mediated inhibition of hippocampal long-term potentiation (LTP) in mice ...
Mariana Vargas-Caballero +11 more
doaj +1 more source
Study of the inhibitory effect of the small molecule Diethylthia tri carbocyanine iodide, as an anti- Alzheimer's candidate drug on human recombinant tau aggregation [PDF]
, 2015 Background and aims: Alzheimer’s disease is a neurodegenerative disorder that is affected by different factors. Forming aggregations of the tau proteins in the brain is one of the most commonly observation in the patients’ brains suffered from this ...
Hasan Sajedi, Reza. +4 more
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