Results 201 to 210 of about 243,600 (356)

The Role and Pathogenesis of Tau Protein in Alzheimer's Disease. [PDF]

Biomolecules
Hong X, Huang L, Lei F, Li T, Luo Y, Zeng M, Wang Z.   +6 more
europepmc   +1 more source

Step‐by‐step monitoring of a magnetic and SERS‐active immunosensor assembly for purification and detection of tau protein [PDF]

, 2019
Viktor Maurer, Claudia Frank, Julian Cedric Porsiel, Sabrina Zellmer, Georg Garnweitner, Rainer Stosch   +5 more
openalex   +1 more source

Initial Distance‐Dependent Mean Force Drives Synaptic Vesicle Motion Toward Fusion Sites in Stimulated Hippocampal Neurons

Advanced Science, EarlyView.
Synaptic vesicle (SV) motion and exocytosis dynamics in the presynaptic terminals of live neurons are intimately linked to synaptic transmission during neuronal activity. In this work, it is revealed that, during electrical stimulation, SVs located farther from their fusion sites exhibit greater straightness and experience larger mean forces directed ...
Gyunam Park, Ji‐Hyun Kim, Hunki Lee, Chungwon Park, Sidong Chen, Luke Bates, Jaeyoung Sung, Hyokeun Park   +7 more
wiley   +1 more source

Cross-linking mass spectrometry for structure analysis of the intrinsically disordered Tau and phosphorylated Tau protein. [PDF]

PLoS Comput Biol
Arsene C, Gates A, Römmert AK, Märtens A, Faustinelli V, Luckau L, O'Connor G.   +6 more
europepmc   +1 more source

The Effect of Duloxetine on Tau Protein and Migration in Breast Cancer Cell Line [PDF]

, 2017
Bahareh Zarrin, Shaghayegh Haghjooy Javanmard, Fariba Samani, Mohamadhasan Tajadini, Maryam Jamady, Neda Esmaeli, Ahmed Ghasemi, Golnaz Vaseghi   +7 more
openalex   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Protocol for the removal of bound endotoxin from tau protein produced in Escherichia coli. [PDF]

STAR Protoc
Shultz A, Mena D, Roy JL, Nulman J, Rauch JN.   +4 more
europepmc   +1 more source

NIR‐Activatable Domino Cascade Catalysis Nanozyme Reactor for Multi‐Mechanism Synergistic Immunotherapy in Bladder Cancer

Advanced Science, EarlyView.
This study presents an intravesical delivery strategy of ferroptosis‐ and immunity‐inducing nanozyme‐loaded thermoresponsive hydrogels (FMCC@PNH) for enhanced bladder cancer therapy. Abstract Current intravesical therapies for bladder cancer after resection are limited by poor tissue penetration, off‐target effects, and insufficient efficacy.
Yongnan Jiang, Qingling Zhang, Yuhan Zhang, Xinlu Yu, Bo Jia, Yulong Dong, Yalong Wu, Kelong Fan, Xinquan Gu, Lei Ji, Wei Jiang, Bin Liu   +11 more
wiley   +1 more source

Evaluation and limitations of the novel chemiluminescent enzyme immunoassay technique for measuring total tau protein in the cerebrospinal fluid in patients with human prion disease: a 10-year prospective study (2011–2020) [PDF]

Kong Weijie, Toshiaki Nonaka, Katsuya Satoh   +2 more
openalex   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source