Results 321 to 330 of about 5,828,673 (370)

The role of small GTPases in Alzheimer's disease tau pathologies. [PDF]

Front Cell Neurosci
Hoegy P, Chen YH, Lu Q.
europepmc   +1 more source

Enhanced Hill's Muscle Model for Tissue‐Engineered Skeletal Muscle and its Application to Reverse‐Action Tweezers Actuation

Advanced Intelligent Systems, EarlyView.
A six‐element viscoelastic model is presented for tissue‐engineered skeletal muscle, addressing the limitations of the conventional Hill's model. By introducing an active branch, the model accurately describes force responses in both elongation and isometric tests and successfully predicts the electrically induced displacement of a reverse‐action ...
Mizuki Nakamura, Masaki Osawa, Akemi Nakayama, Noriyasu Iwamoto, Seiji Takashima, Ken Masuya, Yoshitake Akiyama   +6 more
wiley   +1 more source

Amyloid-β, Tau, and α-Synuclein Protein Interactomes as Therapeutic Targets in Neurodegenerative Diseases. [PDF]

Cell Mol Neurobiol
Mohan Kumar D, Talwar P.
europepmc   +1 more source

Bioinspired Engineering beyond Homeostasis

Advanced Intelligent Systems, EarlyView.
This perspective article introduces systems biology as the unifying theoretical framework behind bioinspired engineering. As an example, it explores how disruptions in multiscale biological systems, associated with pathological states, can be viewed as localized failure modes of biological cooperation showing emergent advantages that can inspire ...
Rosalia Moreddu
wiley   +1 more source

BioID2-Based Tau Interactome Reveals Novel and Known Protein Interactions Associated with Multiple Cellular Pathways. [PDF]

J Proteome Res
Atwa A, Alhadidy MM, Lamp J, Combs B, M Kanaan N.   +4 more
europepmc   +1 more source

Blood α‐Synuclein Separates Parkinson's Disease from Dementia with Lewy Bodies

Annals of Neurology, EarlyView.
Objective Aggregation of misfolded α‐synuclein (aSyn) within the brain is the pathologic hallmark of Lewy body diseases (LBDs), including Parkinson's disease (PD), and dementia with Lewy bodies (DLB) disease. Although evidence exists for aSyn “strains,” conformations with distinct biological properties, biomarkers for PD versus DLB are lacking.
George T. Kannarkat, Rebecca Zack, R. Tyler Skrinak, James F. Morley, Roseanne Davila‐Rivera, Sanaz Arezoumandan, Katherine Dorfman, Kelvin Luk, David A. Wolk, Daniel Weintraub, Thomas F. Tropea, Edward B. Lee, Sharon X. Xie, Ganesh Chandrasekaran, Virginia M.‐Y. Lee, David Irwin, Rizwan S. Akhtar, Alice S. Chen‐Plotkin   +17 more
wiley   +1 more source

Liquor-tau-Proteine, gesamt [PDF]

, 2018
openaire   +2 more sources

Overview of Proteomic Analysis of Amyloid Plaques and Neurofibrillary Tangles in Alzheimer's Disease. [PDF]

Biomolecules
Grewal A, Raikundalia S, Zaia J, Sethi MK.   +3 more
europepmc   +1 more source

Frequency of Microvascular Pathology and Hippocampal Atrophy on Magnetic Resonance Imaging in a Community Study of Alzheimer's Disease with Blood‐Based Biomarkers

Annals of Neurology, EarlyView.
Objective Blood‐based biomarkers for Alzheimer's disease (AD), representing antemortem indicators of AD pathophysiology, have greatly improved the accuracy of diagnosis. However, these biomarkers may not capture a frequent coincident pathology, such as cerebrovascular disease.
Tamil Iniyan Gunasekaran, Danurys Sanchez, Dolly Reyes‐Dumeyer, Rabel Ventura, Clarissa Morales, Mohamad Alshikho, Annie J. Lee, Rafael A. Lantigua, Yian Gu, Lawrence S. Honig, Badri N. Vardarajan, Adam M. Brickman, Richard Mayeux   +12 more
wiley   +1 more source

Impact of Sex and Glial Tau Expression on Heat Shock Protein Induction in a <i>Drosophila</i> Model of Tauopathy. [PDF]

ACS Omega
Whitmore M, Coughlan M, Kahlson MA, Alvarez J, Zebrowski L, Colodner KJ, McMenimen KA.   +6 more
europepmc   +1 more source