Results 331 to 340 of about 5,828,673 (370)

Genetic code expansion and enzymatic modifications as accessible methods for studying site-specific post-translational modifications of alpha-synuclein and tau. [PDF]

Protein Sci
Saleh IG, Shimogawa M, Ramirez J, Abakah B, Venkatesh Y, James HP, Li MH, Louie SA, Lougee MG, Chia WK, Brue C, Cooley RB, Mehl RA, Baumgart T, Mach RH, Eliezer D, Rhoades E, Petersson EJ.   +17 more
europepmc   +1 more source

Synthetic chaperone based on Hsp90-Tau interaction inhibits Tau aggregation and rescues physiological Tau-Microtubule interaction. [PDF]

Nat Commun
Di Lorenzo D, Bisi N, Kaffy J, Ramirez LM, Zweckstetter M, Lequin O, Garfagnini I, Luo J, Hannappel Y, Ennen I, Dodero V, Sewald N, Gelmi ML, Tonali N, Brandt R, Ongeri S.   +15 more
europepmc   +1 more source

Proteomic and non-proteomic changes of presynaptic proteins in animal models of Alzheimer's disease: A meta-analysis 2015-2023. [PDF]

J Alzheimers Dis
Anschuetz A, Schwab K, Harrington CR, Wischik CM, Riedel G.   +4 more
europepmc   +1 more source

Misfolded Tau Protein in the Retina

Open Access Journal of Ophthalmology, 2018
openaire   +1 more source

Tau Enhances Aggregation of S100A9 Protein and Further Association of Its Fibrils. [PDF]

Int J Mol Sci
Krasauskas L, Veiveris D, Žiaunys M, Šulskis D, Sakalauskas A, Smirnovas V.   +5 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Tau protein and tau aggregation inhibitors

Neuropharmacology, 2010
Alzheimer disease is characterized by pathological aggregation of two proteins, tau and Abeta-amyloid, both of which are considered to be toxic to neurons. In this review we summarize recent advances on small molecule inhibitors of protein aggregation with emphasis on tau, with activities mediated by the direct interference of self-assembly.
Eckhard Mandelkow, Bruno Bulic, Eva-Maria Mandelkow, Marcus Pickhardt   +3 more
openaire   +3 more sources

The discovery of tau protein

Cytoskeleton, 2023
AbstractIn January of this year I received an unexpected request from George Bloom to contribute an historical perspective on “the discovery of tau protein,” an event that occurred roughly 50 years ago. My first thought was that it could not have been that long ago, as the memories of what was my first independent scientific discovery are still fresh ...
openaire   +2 more sources

Tau Protein and Zebrafish Models for Tau-Induced Neurodegeneration

Journal of Alzheimer's Disease, 2019
Tauopathies are a specific type of slow and progressive neurodegeneration, which involves intracellular deposition of fibrillar material composed of abnormal hyperphosphorylation of the microtubule associated protein (MAP) tau. Despite many years of intensive research, our understanding of the molecular events that lead to neurodegeneration is far from
Zhi Tang, Yuanting Ding, Chencen Lai, Lei Lijuan   +3 more
openaire   +3 more sources

Tau protein and Alzheimer's disease [PDF]

Neurobiology of Aging, 1994
The etiology of Alzheimer's disease is still unknown. Because the disease is specific for human brain, a rational search for early diagnosis or prevention is very difficult. This calls for the development of cellular models that mimick the degeneration of neurons in AD.
Eckhard Mandelkow, Eva-Maria Mandelkow
openaire   +2 more sources

Phosphorylation of tau protein in tau-transfected 3T3 cells

Molecular Brain Research, 1993
The tau protein of Alzheimer paired helical filaments (PHFs) is aberrantly phosphorylated, as evidenced by its reactivity with several phosphate-dependent antibodies. We sought to identify whether this unusual phosphorylation state exists in tau expressed by transfected NIH 3T3 fibroblasts. Immunoblot analysis of cell clones transfected with constructs
Mathew M.S. Lo, Clay W Scott, Linda A. Sygowski, Claudia B. Caputo, Ann W. Fieles   +4 more
openaire   +3 more sources