Results 211 to 220 of about 63,418 (298)

The Bile Acid Signaling Axis: Deciphering the Roles of FXR and TGR5 in Hepatic Steatosis, Fibrosis, and Cancer

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Bile acids (BAs) serve not only as emulsifiers for lipid digestion but also as essential signaling molecules, governing various physiological and pathological processes through their interaction with the farnesoid X receptor (FXR) and the takeda G protein‐coupled receptor 5 (TGR5).
Jie Liu, Kui Sun, Hongmei Liu, Meiyang Zhu, Chunmeng Li, Yuqi He, Lin Qin   +6 more
wiley   +1 more source

Insights into taurine therapy for periodontitis: Targeting osteocyte ferroptosis to mitigate obesity-exacerbated bone damage. [PDF]

Redox Biol
Chen XG, Zhu XX, Cao CH, Chen YZ, Huo YD, Gan D, Deng DK, Xu M, Qu HL, Chen FM, Tian BM, Li X.   +11 more
europepmc   +1 more source

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Phytotherapy Research, Volume 40, Issue 10, Page 6005-6042, October 2026.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen, Jian Liu, Lei Wan, Fanfan Wang, Yang Li   +4 more
wiley   +1 more source

Mitochondrial DNA A3243G variant-associated MELAS: Recent advances in clinical trials, therapeutic interventions, and disease-modifying strategies. [PDF]

Intractable Rare Dis Res
Chu KY.
europepmc   +1 more source

A Simple Temperature‐Controlled Method for Preserving Viability in Human Pluripotent Stem Cell‐Derived Retinal Organoids During Shipment

FASEB BioAdvances, Volume 8, Issue 10, October 2026.
A lithium‐free temperature‐controlled shipping system (YOTI) stabilizes physiologic temperatures during overnight transport of mature human iPSC‐derived retinal organoids. Compared to conventional ambient shipping, YOTI reduces temperature fluctuations, preserves retinal lamination, decreases cell death, and maintains rod photoreceptor marker ...
Karen Cusato, Matthew J. Tarchick, Michael Ha, Jessica R. Onyak, Aimee C. Saunders, Joseph A. Brzezinski IV, Jordan M. Renna, M. Natalia Vergara   +7 more
wiley   +1 more source

Taurine reverses long-term memory deficits caused by LPS induced neuroinflammation. [PDF]

BMC Neurosci
Haskel MVL, da Silva Vequi LS, Flauzino MWP, da Silva Correa V, Oliveira CS, Pereira ME, de Gregório E, Bonini JS, da Silva WC.   +8 more
europepmc   +1 more source

Inhibiting Glutaminase Reverses Senescence‐Associated Mitochondrial Dysfunction and Skeletal Muscle Decline

Aging Cell, Volume 25, Issue 10, October 2026.
Pharmacological inhibition of glutaminase with drug CB‐839 restores mitochondrial function in senescent myoblasts and enhances muscle strength and endurance in progeria mice. ABSTRACT Age‐associated loss of skeletal muscle mass and function, also known as sarcopenia, is closely linked to mitochondrial dysfunction.
Hamsa Vardini Senthil Kumar, Debanik Choudhury, Pedro Lei, Pihu Mehrotra, Shahryar Shahini, Sydney Swedick, John Toftegaard, Stelios T. Andreadis   +7 more
wiley   +1 more source

Synergistic application of taurine and spermidine enhances wheat tolerance to neodymium stress through redox homeostasis, metabolic adjustment, and nutrient regulation. [PDF]

Plant Signal Behav
Iqbal R, Mehmood H, Majeed A, Murtaza G, Rebouh NY, Alotaibi MS, Alotaibi SS, Ullah S, Huseynova A, Ali S.   +9 more
europepmc   +1 more source

Ya‐Jie‐Sha‐Ba Decoction Regulates Arachidonic Acid Metabolism to Treat Alcohol‐Associated Liver Disease by Activating PPARα–CYP4A14 Axis: Insights From Multi‐Omics Analysis and Experimental Validations

Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Ya‐Jie‐Sha‐Ba decoction (YJSB), a traditional Dai medicinal formulation, has been widely used by the Dai ethnic group and has shown efficacy in alleviating alcohol‐associated liver disease (ALD). However, the molecular mechanism of YJSB in the management of ALD remains unclear.
Dehong Ma, Xia Chen, Huixian Dao, Hongyu Deng, Yingcheng Guo, Hui Yang, Yuanyuan Chen, Congmei Zhang, Yuan Long, Weibo Wen, Yinghong Zhao, Huantian Cui   +11 more
wiley   +1 more source

The miR‐145‐5p/NRF2/SLC7A11 axis regulates ferroptosis‐mediated renal tubular epithelial cell injury in diabetic nephropathy

Journal of Diabetes Investigation, Volume 17, Issue 10, Page 1667-1685, October 2026.
Suppression of miR‐145‐5p alleviates DN‐associated renal tissue damage by inhibiting NRF2/SLC7A11‐mediated ferroptosis of RTECs. ABSTRACT Purpose This study aimed to investigate the molecular mechanism by which the miR‐145‐5p/NRF2/SLC7A11 axis regulates ferroptosis‐mediated renal tubular epithelial cell (RTEC) injury in diabetic nephropathy (DN ...
Ganlin Wu, Yu Fang, Meirong Xu, Zuopeng Lu, Yu Cao, Yana Gao   +5 more
wiley   +1 more source