Results 191 to 200 of about 63,418 (298)

Metabolic Signatures of Aging and Gametogenesis in Hydra oligactis. [PDF]

open access: yesAging Cell
Marami-Zonouz N   +6 more
europepmc   +1 more source

Hepatic HIF2α Modulates Extra‐Hepatic Disease‐Associated Phenotypes During Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesComprehensive Physiology, Volume 16, Issue 5, October 2026.
High fat, high fructose, high cholesterol “GAN” diet feeding in mice induces MASLD, cardiac dysfunction, loss of lean mass, and hyperinsulinaemia. Hepatocyte‐specific deletion of HIF2α also causes cardiac dysfunction and loss of lean mass but prevents GAN induced hyperinsulinaemia and cardiac sympathetic dominance without preventing MASLD.
Lorenz M. W. Holzner   +15 more
wiley   +1 more source

Gallstone formation and hepatobiliary tumour risk: Clinical implications of the bile acid–gut microbiota axis

open access: yesClinical and Translational Discovery, Volume 6, Issue 5, October 2026.
1. Irregular dietary patterns (e.g., late breakfast, reduced meal frequency) upregulate the bai gene cluster by disrupting cholecystokinin (CCK) release rhythms and gut microbiota circadian rhythms, leading to increased production of secondary bile acids, particularly DCA. High‐carbohydrate dietary patterns increase gallstone risk (OR = 1.329).
Rui Li   +6 more
wiley   +1 more source

Soil Moisture and Prey Life Cycles Promote Seasonal Dietary Shift in a Grassland‐Breeding Migratory Shorebird

open access: yesEcology and Evolution, Volume 16, Issue 10, October 2026.
In this study, we utilized DNA metabarcoding of 207 fecal samples to describe the diet of flock‐foraging godwits in southwest Friesland, the Netherlands, during pre‐nesting (March) and post‐nesting (May–June) periods. To assess whether dietary changes were resource or selectivity based, we simultaneously quantified soil macrofauna biomass and measured ...
Renée Veenstra   +6 more
wiley   +1 more source

Trigonelline Alleviates Neuroinflammation in AAV‐SynA53T Parkinson's Disease Model Mice: Involvement of PI3K/AKT–NF‐κB Signaling and Gut Microbial‐Metabolic Remodeling

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
Trigonelline alleviated motor deficits, α‐synuclein‐associated pathology, and neuroinflammatory changes in AAV‐SynA53T mice. These effects were accompanied by reduced PI3K/AKT–NF‐κB signaling activity, improved intestinal barrier‐associated features, and gut microbiota–metabolome remodeling.
Mozi Chen   +10 more
wiley   +1 more source

Effects of taurine on skeletal muscle in senescence-accelerated mice and C2C12 myoblasts and myotubes. [PDF]

open access: yesAmino Acids
Huang Y   +9 more
europepmc   +1 more source

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