Results 171 to 180 of about 91,409 (249)

Taurine-driven chemotaxis and metamorphosis in ascidian tadpole larvae. [PDF]

Sci Adv
Yang LK, Qin Q, Zhang J, Zhang Z, Yu H, Zhao C, Dong B.   +6 more
europepmc   +1 more source

Spectral Representation of Neurochemicals With Phase, Frequency Offset, and Lineshape Invariance: Application to JPRESS for In Vivo Concentration and T2 Mapping by Deep Learning

Magnetic Resonance in Medicine, Volume 95, Issue 6, Page 3052-3064, June 2026.
ABSTRACT Purpose Using artificial intelligence neural networks to generate a representation that maps the input directly to neurochemical concentrations and metabolite‐level average transverse relaxation times (T2). Methods The proposed model used time‐domain JPRESS data as input and was trained to be invariant to phase shifts, frequency offsets, and ...
Yan Zhang, Jun Shen
wiley   +1 more source

Caloric Restriction and Dietary Taurine Regulate Taurine Homeostasis Through Distinct Tissue-Specific Mechanisms in Mice. [PDF]

Mol Nutr Food Res
Gregor A, Auñon-Lopez A, Zebeli Q, Pignitter M, Duszka K.   +4 more
europepmc   +1 more source

Higher sensitivity to ouabain‐induced toxicity in human induced pluripotent stem cell‐derived cardiomyocytes than human adult heart tissue despite similar Na+/K+‐ATPase pump current amplitudes

British Journal of Pharmacology, Volume 183, Issue 11, Page 3093-3110, June 2026.
Abstract Background and Purpose Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CM) have gained interest as a pharmacological model but their immaturity leads to uncertainty regarding translation. We studied the key player in maintaining ionic homeostasis, the Na+/K+‐ATPase (NKA), in hiPSC‐CM.
Djemail Ismaili, Paavo Virtanen, Junsoo Im, Paul Brunnbauer, Umber Saleem, Muhammed Ikbal Sönmez, Carl Schulz, Margaret Nandudu, Joris Winters, Cristina E. Molina, Johannes Petersen, Monika Stoll, Ulrich Schotten, Arne Hansen, Thomas Eschenhagen, Jussi T. Koivumäki, Torsten Christ   +16 more
wiley   +1 more source

Frailty phenotype reveals heterogeneity in aging and distinct taurine associations. [PDF]

NPJ Aging
Kim A, Keener R, Omdahl A, Bene M, Westbrook R, Le A, Zhang C, Khare P, Khadeer M, Ferrucci L, Moaddel R, Battle A, Abadir P.   +12 more
europepmc   +1 more source

Temporal Metabolomics Profiling Reveals Liver Metabolic Control in Single and Repeated Exhaustive Exercise in Murine Models

The FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Temporal metabolomics profiling reveals divergent liver recovery trajectories between single and repeated exhausted exercise stress. Single exhaustive exercise (SEE) demonstrates transient metabolic perturbations resolving within 24 h. In contrast, repeated exhaustive exercise (REE) triggers sustained metabolic remodeling that persists beyond the ...
Jining Yang, Dawei Wang, Hui Shen, Yundong Xia, Hedong Lang, Wenxin Zhou, Long Yi, Mantian Mi   +7 more
wiley   +1 more source

Transcriptomic profiling of chlorogenic acid and taurine treatment in human skin cells provides insights into cellular senescence mechanisms. [PDF]

Front Mol Biosci
Kim B, Shin JG, Hong IS, Ahn Y, Seo JY, Shin JY, Lee S, Jun SH, Jeong ET, Jo H, Park MS, Kim DS, Kang NG, Kim Y, Won HH.   +14 more
europepmc   +1 more source

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo, Linjuan Feng, Shiying Li, Lik Hang Hugo Tse, Xuehan Wang, Xingyang Zhao, Shaoheng Ma, Xin Li, Yanjuan Gu, Wing‐Tak Wong   +9 more
wiley   +1 more source

4-Aminopyridine reveals presynaptic GABA actions in rat sympathetic ganglia [PDF]

, 1981
Galvan, Martin, Grafe, Peter, Ten Bruggencate, Gerrit   +2 more
core  

Chemical Characterization of Toxic Elements in Plastic Utensils: Key Insights and Health Impacts

CLEAN – Soil, Air, Water, Volume 54, Issue 5, May 2026.
Toxic elements in plastic utensils are assessed using portable X‐ray fluorescence and specific migration tests with water and 3% acetic acid as food simulants. Cadmium, lead, arsenic, and mercury are detected in the utensils, and migration results show exceedances of specific migration limits, particularly for lead, mercury, and cadmium. These findings
Elizeu Chiodi Pereira, Lucas Takeshi Shimizu Hossokawa, Isabelle Nogueira Leroux, Aline de Carvalho Elias, Maciel Santos Luz, Kelly Polido Kaneshiro Olympio   +5 more
wiley   +1 more source